Can precise radiation help when breast cancer spreads to just a few places?
NCT ID NCT07397585
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether a precise type of radiation called SBRT can help people with breast cancer that has spread to only a few spots in the body (oligometastatic). Researchers will review medical records from 300 patients to see if SBRT improves how long the cancer stays under control and how long patients live. The goal is to gather more evidence on whether this non-invasive treatment is a good option alongside standard therapies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- stereotactic body radiotherapy (SBRT)
- What this could lead to
- If this study shows SBRT helps control the cancer and extend survival, it could support using targeted radiation as a standard treatment for limited metastatic breast cancer.
- What could go wrong
- This is a retrospective study, so it looks back at past data rather than testing a new treatment in a controlled way. Results may be less reliable and not prove cause and effect.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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A.O.U. "G. Martino" - Università degli Studi di Messina
NOT_YET_RECRUITINGMessina, Messina, 98124, Italy
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Aorn San Pio
NOT_YET_RECRUITINGBenevento, Benevento, 82100, Italy
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Azienda Ospedaliera San Giovanni Addolorata
NOT_YET_RECRUITINGRoma, RM, 00184, Italy
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Azienda Ospedaliera Sant'Andrea
NOT_YET_RECRUITINGRoma, Roma, 00189, Italy
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Azienda Ospedaliera Universitaria Careggi
NOT_YET_RECRUITINGFlorence, Firenze, 50134, Italy
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Azienda Ospedaliera Universitaria Pisana
NOT_YET_RECRUITINGPisa, PI, 56124, Italy
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Civico Palermo
NOT_YET_RECRUITINGPalermo, Palermo, 90127, Italy
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Fondazione I.R.C.C.S Istituto Nazionale Tumori di Milano
RECRUITINGMilan, MILANO, 20133, Italy
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Fondazione PTV Policlinico Tor Vergata
NOT_YET_RECRUITINGRoma, Roma, 00133, Italy
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Fondazione Policlinico Universitario, Campus-Biomedico
RECRUITINGRoma, Roma, 00128, Italy
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Humanitas Gavazzeni
RECRUITINGBergamo, Bergamo, 24125, Italy
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IEO
NOT_YET_RECRUITINGMilan, Milano, 20141, Italy
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INT IRCCS Fondazione G. Pascale
RECRUITINGNaples, Napoli, 80131, Italy
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IRCCS Centro di Riferimento Oncologico di Aviano
NOT_YET_RECRUITINGAviano, Pordenone, 33081, Italy
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IRCCS Humanitas Research Humanitas
RECRUITINGRozzano, MILANO, 20089, Italy
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IRCCS Ospedale San Raffaele
NOT_YET_RECRUITINGMilan, Milan, 20132, Italy
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Irccs Crob
RECRUITINGRionero in Vulture, PZ, 85028, Italy
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Irccs Ospedale Policlinico San Martino
NOT_YET_RECRUITINGGenova, Genova, 16132, Italy
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Istituto Oncologico Veneto
NOT_YET_RECRUITINGPadova, PD, 35128, Italy
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Ospedale Maggiore della Carita
RECRUITINGNovara, NOVARA, 28100, Italy
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Ospedale Perrino
NOT_YET_RECRUITINGBrindisi, BR, 72100, Italy
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Radioterapia Oncologica - Ospedale Sanata Chiara
NOT_YET_RECRUITINGTrento, TRENTO, 38122, Italy
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Responsible Research Hospital
RECRUITINGCampobasso, CB, 86100, Italy
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S.C. Radioterapia Oncologica - Azienda Ospedaliera Santa Maria Terni
NOT_YET_RECRUITINGTerni, TR, 05100, Italy
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S.C. Radioterapia Oncologica ASL Taranto
NOT_YET_RECRUITINGTaranto, Taranto, 74100, Italy
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Spedali Civili
RECRUITINGBrescia, BS, 25123, Italy
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UOC Radioterapia Ospedale San Filippo Neri
NOT_YET_RECRUITINGRoma, RM, 00135, Italy
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Uo Radioterapia Aor San Carlo
NOT_YET_RECRUITINGPotenza, PZ, 85100, Italy
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