Can immunotherapy stop colorectal Cancer's return?
NCT ID NCT07058012
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if immunotherapy drugs (cemiplimab, fianlimab, and REGN7075) can clear leftover cancer DNA in the blood of colorectal cancer patients after surgery and chemotherapy. The goal is to delay or prevent the cancer from coming back. About 79 adults with stage II/III colorectal cancer who still have cancer DNA in their blood will participate.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Allegheny General Hospital
RECRUITINGPittsburgh, Pennsylvania, 15212, United States
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Ballad Health Cancer Center - Kingsport
RECRUITINGKingsport, Tennessee, 37660, United States
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Bon Secours St. Francis Medical Center
RECRUITINGMidlothian, Virginia, 23114, United States
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First Health of the Carolinas
RECRUITINGPinehurst, North Carolina, 28374, United States
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Missouri Baptist
RECRUITINGSt Louis, Missouri, 63131, United States
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University of Florida
RECRUITINGGainesville, Florida, 32611, United States
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University of Iowa - Holden Comprehensive Cancer Center
RECRUITINGIowa City, Iowa, 52242, United States
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University of Kansas Cancer Center
RECRUITINGKansas City, Kansas, 66160, United States
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Virginia Commonwealth University - Massey
RECRUITINGRichmond, Virginia, 23298, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Engineered virus joins forces with immunotherapy to fight resistant cancers
- DNA 'Crystal Ball' may spot return of colorectal cancer