Yonsei University

This study aims to find the safest duration for patients with advanced kidney disease to take two blood-thinning medications after receiving a heart stent. Researchers will compare different treatment lengths to see which one best prevents heart attacks and strokes while causing …

This study is testing a three-part treatment for people with advanced head and neck cancer linked to HPV that has come back or spread. The treatment combines a DNA vaccine designed to target the virus, an immune-boosting drug (GX-I7), and an established immunotherapy (nivolumab).…

This study is testing whether a motivational chatbot app can help people who drink too much alcohol cut back. For four weeks, half of the 220 participants will use the app, while the other half waits. Researchers will compare how much alcohol each group drinks over 16 weeks to se…

This study is testing a specialized type of radiation called carbon ion radiotherapy for people with liver cancer that has come back or didn't fully respond to a previous treatment called TARE. The goal is to see if this precise radiation can control the tumor while causing fewer…

This study compares two different methods doctors use when opening blocked arteries in the lower legs of patients with severe circulation problems and non-healing wounds. One method uses standard imaging (angiography), while the other adds a special pressure-measuring wire to get…

This study is testing a home-based monitoring system to see if it helps people recovering from stroke improve their walking and daily activity. The system includes smart insoles, a wrist-worn activity tracker, and a mobile app to give feedback during a 6-week exercise program. Re…

This study compares two surgical approaches for early-stage breast cancer: robot-assisted nipple-sparing mastectomy versus traditional open surgery. Both approaches include immediate breast reconstruction. The trial aims to determine if the robotic technique provides similar canc…

This study is testing whether placing a pacemaker lead in a specific area of the heart (Left Bundle Branch Area Pacing) is better than the standard placement (Right Ventricular Pacing) for patients who need their pacemaker to work a lot of the time. Researchers will follow 450 pa…

This study is testing if a two-drug cholesterol-lowering combination works better than the standard single drug to prevent future heart attacks, strokes, or death in people who have had a stent placed. It will enroll over 4,300 adults who recently received a new type of drug-coat…

This study is testing whether a targeted drug called lazertinib, given alone or with standard chemotherapy before surgery, can better shrink tumors in people with early-stage lung cancer that has a specific genetic change (EGFR mutation). The goal is to see if this pre-surgery tr…

This study is testing how safely a specific drug-coated heart stent can be expanded to fit arteries that are wider at one end than the other. Researchers will use a special high-resolution camera inside the artery to check for any damage to the stent after it is stretched. The go…

This study is testing whether a specific approach to managing blood pressure after a stroke clot is removed helps people recover better. It will compare two strategies: one that slightly raises blood pressure and another that follows current standard guidelines. The goal is to se…

This study is testing whether adding a new drug called SLC-3010 to an existing cancer drug (axitinib) works better than using axitinib alone. It is for adults with advanced kidney cancer that has worsened after their first treatment. The main goal is to see if the combination hel…

This study is testing whether a smartphone app can help people maintain a normal heart rhythm after a procedure for atrial fibrillation (AFib). 500 patients in South Korea who have received a specific new ablation treatment will be randomly assigned to either use the app for remi…

This study is testing whether adding a precise form of radiation, called carbon ion radiotherapy, to a standard two-drug treatment helps people with advanced liver cancer. It aims to see if this combination can control the cancer for longer and improve survival compared to the dr…

This study is testing whether adding the immunotherapy drug nivolumab after standard chemoradiation treatment can help prevent cancer from returning in patients with locally advanced nasopharyngeal carcinoma (a type of throat cancer). The trial will enroll 57 adults who have comp…

This study is testing whether carbon ion radiotherapy can help frail pancreatic cancer patients who are too weak for surgery or chemotherapy. The treatment uses a special type of radiation that may better target tumors while sparing healthy tissue. Researchers will track survival…

This study aims to find out whether aspirin or clopidogrel works better at preventing blood clots from forming on new heart valves after a TAVR procedure. Researchers will compare these two common blood thinners in 254 patients who have received a new aortic valve for severe narr…

This study aims to see if a specific enzyme replacement therapy (agalsidase alfa) can reduce inflammation in the hearts of people with Fabry disease. Researchers will use detailed heart scans (PET-CMR) to measure inflammation in 25 patients before they start treatment and again a…

This study is testing a new software tool that creates a 'roadmap' of the heart's arteries on the X-ray screen. The goal is to see if this map helps doctors perform two specific pressure tests (FFR and iFR) more quickly and easily during a standard angiogram. Researchers will mea…

This study is testing a new ultrasound imaging technique called Fluctuational Imaging (FLI) to see if it can accurately diagnose hepatic hemangiomas, which are common benign liver tumors. Researchers will enroll 400 adults with liver lesions to compare FLI results against standar…

This study aims to find the safest and most effective dose of a common cholesterol-lowering drug (statin) for preventing heart disease in healthy adults aged 70 and older. It will compare a low dose to a moderate dose, focusing on side effects like muscle pain. The goal is to pro…

This study aims to understand how a wearable robotic hip exoskeleton changes the way people walk. Researchers will measure step length, walking speed, joint movement, and muscle activity in 15 healthy adults while they use the device. The goal is to gather basic knowledge about h…

This study is creating a registry to observe the safety and success of a newer technique for accessing arteries in the wrist during heart procedures. It will enroll 3,600 adults who need a heart scan or intervention and have a suitable artery. The goal is to gather real-world dat…

This study aims to see if data from smart shoe insoles and other pre-surgery information can predict how well patients will recover after a total knee replacement. Researchers will observe 200 patients, analyzing their walking patterns before surgery and their reported pain and m…