Yonsei University

This phase 2 trial tested two chemotherapy drugs, paclitaxel and carboplatin, given before surgery to 79 people with locally advanced head and neck cancer. The goal was to see how well the drugs shrink tumors before surgery. The main measure was a major pathologic response, meani…

This study tested whether adding the immunotherapy drug durvalumab to standard chemotherapy (doxorubicin) could help people with advanced soft tissue sarcoma that has spread or come back. The trial included 44 adults whose cancer could be measured and who were healthy enough for …

This study looked at a special drug-coated stent (Genoss DES) in 200 people with coronary artery disease who are at high risk for heart attacks. The stent slowly releases sirolimus to help keep the artery open. Researchers tracked how many patients had heart-related death, heart …

This study followed 204 people with coronary artery disease who received the Ultimaster stent, a thin mesh tube coated with a drug that slowly releases to prevent arteries from clogging again. The stent's coating dissolves over 3-4 months. Researchers tracked safety and effective…

This study looked at 3048 adults with heart or blood vessel disease to see if lowering LDL ('bad') cholesterol to a very low level (below 55 mg/dL) is better than the standard target (below 70 mg/dL). Participants received either a statin alone or a statin plus ezetimibe. The goa…

This study tested whether wearing a small heart monitor (MEMO Patch PLUS) for 8 to 14 days finds more cases of hidden atrial fibrillation than wearing it for just 1 day. About 1,000 adults aged 75 or older (or with other stroke risk factors) wore the patch. The goal was to see if…

This study tested whether the drug fexuprazan can prevent or control stomach inflammation (gastritis) in people who need to take systemic steroids for at least 4 weeks. 42 adults with respiratory diseases were randomly assigned to take either fexuprazan or the standard drug lanso…

This study tested whether a special monitor that tracks pain signals during anesthesia can help doctors use less pain medicine during knee surgery. 54 adults having arthroscopic knee surgery were randomly assigned to receive either standard monitoring or the extra pain monitor. T…

This study looked at whether a combination inhaler (tiotropium/olodaterol) can improve exercise capacity in people with COPD who have overinflated lungs. 44 adults used the inhaler for 4 weeks, and researchers measured changes in oxygen use during exercise, heart function, and qu…

This study tested whether a single session of radiofrequency treatment with continuous water cooling could improve jawline contour and facial volume in 22 women aged 38-50. Participants received one treatment and were followed for 8 weeks. The goal was to see if the device could …

This study tested whether a device called transcranial direct current stimulation (tDCS) can help people with mild to moderate depression. The device sends a tiny electrical current through the scalp to regulate brain activity. Researchers enrolled 198 adults and measured changes…

This completed Phase 4 trial tested whether a skin booster made from human tissue (phADM) plus hyaluronic acid works better than hyaluronic acid alone for wrinkles and skin texture. Twenty adults received three injections on one cheek with the combination and on the other cheek w…

This study aims to find the best dose of remifentanil, a fast-acting opioid, for inserting a laryngeal mask airway (a type of breathing tube) during anesthesia with remimazolam. Researchers will test different doses in 60 adults having short elective surgeries, adjusting the dose…

This completed study looked at 50 people with advanced head and neck cancer that had stopped responding to chemotherapy. Researchers gave them the drug nivolumab and analyzed their tumors and blood to find biological markers that could predict who would respond best. The goal was…

This study looked at 58 adults having surgery under general anesthesia. Researchers compared two breathing techniques—tidal volume breathing (normal breaths) and vital capacity breathing (deep breaths)—while using high-flow nasal oxygen before anesthesia. The goal was to see whic…

This study looked at over 31,000 cancer patients to see if an AI-enhanced electrocardiogram (ECG) could predict heart damage caused by chemotherapy. Researchers analyzed existing ECGs taken before treatment to see if the AI could identify those at risk. The goal is to develop a s…

This study aimed to find immune-related biomarkers that could predict how well patients with non-small cell lung cancer respond to the drug atezolizumab. Researchers analyzed blood and tumor samples from 100 participants to track immune cell changes and genetic markers. The goal …

This study tested whether inhaling iloprost, a drug that widens blood vessels in the lungs, can improve oxygen levels in obese patients during one-lung ventilation for lung surgery. 78 participants were randomly assigned to receive either iloprost or a saltwater placebo. The rese…

This study looked at whether using a thin, 7-French sheath through a small artery in the wrist is safe and effective for opening blocked heart arteries. 100 adults with heart disease took part. The goal was to see if this approach causes fewer bleeding or artery problems while st…

This study compared radiation exposure to doctors during heart procedures (coronary angiography and stenting) using two different arm artery approaches: the left distal radial artery and the conventional right radial artery. Over 1,000 patients participated. The goal was to see i…

This study looked at 150 adults who had heart valve surgery to see if a protein called erythroferron is linked to changes in hemoglobin levels after surgery. Hemoglobin is important for carrying oxygen in the blood, and low levels (anemia) can slow recovery. The researchers measu…

This study looked at 135 adults having off-pump coronary artery bypass surgery to see if vitamin D levels affect hemoglobin (a protein in red blood cells) recovery after surgery. Researchers measured vitamin D and a hormone called hepcidin, which controls iron use. The goal was t…