Yonsei University

This study tests a drug called T-DXd (Enhertu) in 27 adults with advanced HER2-mutant lung cancer that has spread to the brain but is not causing symptoms. The main goal is to see how long the cancer in the brain stays under control. Participants receive the drug intravenously an…

This study compares two different cholesterol-lowering drug combinations (rosuvastatin/ezetimibe vs. atorvastatin/ezetimibe) in 200 adults who have received a heart stent. The goal is to see which combo better keeps LDL cholesterol below 55 mg/dL and causes fewer side effects lik…

This study tests whether adding chemotherapy to the targeted drug lazertinib can help people with a specific type of advanced lung cancer (EGFR-mutant non-small cell lung cancer) whose cancer stopped responding to lazertinib alone. About 87 adults will receive the combination and…

This study is testing a special drug-coated stent (Cre8) in 300 people with long blockages in their heart arteries. The goal is to see if the stent is safe and effective at keeping the artery open. Participants must be 19 or older and have a blockage at least 30 mm long.

This study tests whether combining an HPV DNA vaccine with other drugs can shrink tumors in people with advanced head and neck cancer caused by HPV types 16 or 18. Participants receive the treatment before surgery, and doctors check how much of the tumor is killed. The goal is to…

This study looks at how much a specific type of heart stent can be safely expanded beyond its normal size. Researchers used a special camera to measure the stent in 30 adults with narrowed arteries. The goal is to find the safest way to use stents in tricky cases where artery siz…

This study looks at whether a common diabetes medicine called SGLT2 inhibitor can help people with type 2 diabetes who have had a heart attack. Researchers will compare health records of 200,000 people in Korea who took either an SGLT2 inhibitor or another diabetes drug after the…

This study aims to find immune system markers that can predict how well the drug nivolumab works in people with recurrent or metastatic head and neck squamous cell carcinoma. Researchers will analyze tumor tissue and blood samples from 50 participants to look for these markers. T…

This study is collecting information from 3,600 adults who need heart tests or treatments. Doctors will use a small artery in the wrist instead of the groin. The goal is to see how often the procedure works and if there are any problems.

This phase 2 trial is testing the drug durvalumab in 25 people with operable non-small cell lung cancer to see how it changes the immune system before their tumor is removed. The main goal is to measure how many tumors shrink or have fewer than 10% viable cancer cells after treat…