Lung cancer combo shows promise after first drug fails
NCT ID NCT05786430
First seen Feb 01, 2026 · Last updated Jun 12, 2026 · Updated 14 times
Summary
This study tests whether adding chemotherapy (pemetrexed and carboplatin) to the targeted drug lazertinib can help people with a specific type of advanced lung cancer (EGFR-mutant non-small cell lung cancer) whose cancer worsened while on lazertinib alone. About 87 adults will receive the combination to see if it delays cancer growth. The goal is to find a new treatment option when the first targeted therapy stops working.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Yonsei University Health System, Severance Hospital
Seoul, South Korea
Conditions
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