HPV vaccine combo shows promise in shrinking head and neck tumors before surgery

NCT ID NCT05286060

First seen Feb 12, 2026 · Last updated May 13, 2026 · Updated 14 times

Summary

This study tests whether combining an HPV DNA vaccine with other drugs can shrink tumors in people with advanced head and neck cancer caused by HPV types 16 or 18. Participants receive the treatment before surgery, and doctors check how much of the tumor is killed. The goal is to see if this approach improves outcomes for patients who have not had chemotherapy before.

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Contacts and locations

Locations

  • Yonsei University Health System, Severance Hospital

    Seoul, South Korea

Conditions

Explore the condition pages connected to this study.