Heart patients get stronger combo pill after stent surgery
NCT ID NCT05782777
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether taking ezetimibe along with a high-dose statin (atorvastatin) works better than the statin alone for people who have had a heart stent placed. About 4,300 participants will be followed for three years to see if the combination reduces deaths, heart attacks, strokes, or the need for more procedures. The goal is to lower LDL cholesterol more aggressively and improve long-term heart health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ezetimibe and atorvastatin (combination therapy) versus atorvastatin alone
- What this could lead to
- If it works, this could show that adding ezetimibe to a high-dose statin reduces the risk of heart attacks, strokes, and death after stent placement.
- What could go wrong
- This is a large but early-stage trial with no phase designation. The benefit may be small or not outweigh the risks of side effects like muscle pain or liver issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Yonsei University Health System, Severance Hospital
RECRUITINGSeoul, South Korea