New study tests smarter way to open blocked leg arteries
NCT ID NCT06879561
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two methods for opening blocked arteries in the lower leg in people with chronic limb-threatening ischemia, a severe condition that can lead to amputation. One group gets standard balloon angioplasty guided by X-ray images (angiography). The other group uses a special pressure wire to ensure the artery is fully opened. The goal is to see which method better restores blood flow and helps wounds heal. About 100 adults will take part, and they will be followed for 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pressure wire-guided balloon angioplasty
What this could lead to
If successful, this could show that using a pressure wire during leg artery treatment leads to better blood flow and faster wound healing for people with severe leg artery disease.
What could go wrong
This is a small, early-stage trial with only 100 participants, so results may not apply to everyone. The pressure wire adds complexity and may not improve outcomes over standard angiography.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Division of Cardiology, Severance Cardiovascular hospital Department of Internal Medicine, Yonsei University College of Medicine
RECRUITINGSeoul, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••