New pacing technique may lower heart failure risk in pacemaker patients

NCT ID NCT05585411

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests if a newer pacing method, left bundle branch area pacing, is better than standard right ventricular pacing for people who need a pacemaker. Researchers will compare outcomes like death, heart failure, and heart damage in 450 participants over two years. The goal is to see if the newer method can prevent complications from long-term pacing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Left bundle branch area pacing (a procedure to place a pacemaker lead in a specific heart area)

What this could lead to

If successful, this could show that a newer pacing method reduces the risk of heart failure and death compared to standard pacing.

What could go wrong

This is an early-stage comparison study with 450 participants, so results may not apply to all patients. The procedure itself carries standard risks of pacemaker implantation, such as infection or lead displacement.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrioventricular block Bradycardia heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bucheon Sejong Hospital

    RECRUITING

    Bucheon-si, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chungbuk National University Hospital

    RECRUITING

    Chungju, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GyeongSang National University Changwon Hospital

    RECRUITING

    Changwon, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kyunghee University hospital

    RECRUITING

    Seoul, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seoul National University Hospital

    RECRUITING

    Seoul, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seoul Saint Mary's Hospital

    RECRUITING

    Seoul, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yonsei University Health System, Severance Hospital

    NOT_YET_RECRUITING

    Seoul, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••