Tongji Hospital

This study is for people with advanced bile duct or pancreatic cancer who are experiencing significant pain. It aims to see if starting standard cancer drugs at the same time as a specialized pain-blocking injection (Celiac Plexus Block) works better than usual care. Researchers …

This study is testing a combination of an immunotherapy drug (tislelizumab) and a traditional Chinese herbal granule (Huaier) as the first treatment for advanced liver cancer that cannot be removed by surgery. It will involve 94 patients to see if this combo can shrink tumors, co…

This study is testing whether adding two newer drugs (sintilimab and pirtobrutinib) to standard chemotherapy (methotrexate and rituximab) works better for people with newly diagnosed primary central nervous system lymphoma (PCNSL), a rare brain cancer. Researchers will compare th…

This study is testing whether adding a procedure to remove lymphoid tissue in the back of the nose during standard sinus surgery provides better long-term control of inflammation and reduces polyp recurrence. Thirty-two adults with chronic sinusitis and nasal polyps will be rando…

This large study is testing a new, less invasive procedure for treating a severe type of stroke caused by bleeding in the brain. It compares a precise surgery to drain the blood clot using a special drug against standard medical care. The main goal is to see if this approach help…

This study is testing how well glycerol phenylbutyrate controls ammonia levels in Chinese children with rare urea cycle disorders over five years. It will enroll 40 children aged 0-18 who haven't used this medication recently. Researchers will track blood ammonia, growth, brain d…

This study is testing a new approach to prevent early-stage liver cancer from coming back after surgery. An artificial intelligence (AI) model will analyze patient scans and data to predict who is at high risk for recurrence. Those high-risk patients will then receive a personali…

This early-stage study is testing a new one-time treatment called V001-BCMA for people with severe autoimmune diseases that have not responded to standard therapies. The treatment uses a patient's own modified immune cells (CAR-T cells) to target and remove harmful B cells that d…

This early-stage study is testing a new treatment called KD01, which is a modified virus designed to infect and destroy bladder cancer cells. It is given directly into the bladder of patients with high-risk non-muscle-invasive or muscle-invasive bladder cancer. The main goals are…

This study is a registry that will track 200 adults in China who have a specific type of neuromyelitis optica spectrum disorder (NMOSD) and are already receiving a monoclonal antibody treatment. The goal is to see how well these treatments work and how safe they are in real-world…

This study is testing whether a special nutritional formula given to infants around the time of their biliary atresia surgery can help them grow better and improve their recovery. It will compare this special formula to standard feeding in 120 infants under 3 months old at multip…

This early-stage study is testing a new treatment called KD01, which is a specially engineered virus designed to infect and kill cancer cells. It is being given as a direct injection to women with cervical or endometrial cancer who have not responded to other treatments. The main…

This study is testing if a new anesthetic drug called Ciprofol is better than the standard drug, propofol, at preventing heart injury in patients having lung surgery. It will involve over 1,000 adults aged 45-80 undergoing common lung procedures. The main goal is to see if Ciprof…

This study is testing whether two different versions of a traditional Chinese medicine pill work equally well for people who have just had a stroke. Researchers will follow 100 stroke patients for about three months to see which pill helps them recover better in terms of movement…

This early-stage trial is testing whether tiny particles derived from human neural stem cells, called NouvSoma001, can help control neuromyelitis optica spectrum disorders (NMOSD). The study will first find a safe dose by giving the treatment via spinal tap to small groups, then …

This study is testing a new four-drug combination for people with advanced bile duct cancer that cannot be removed by surgery. All participants will receive the same treatment, which adds two new drugs (adebrelimab and simvastatin) to standard chemotherapy. The main goal is to se…

This study is testing the safety and effectiveness of the drug secukinumab in 100 Chinese adults with active ankylosing spondylitis, a painful inflammatory spine disease. Participants have not gotten enough relief from standard anti-inflammatory drugs and have not tried advanced …

This study is testing if a newer drug called Telitacicept is better and safer than the standard treatment, Cyclophosphamide, for controlling lung scarring in people with early lupus. It will involve 100 adults who have both lupus and signs of lung disease. The main goal is to see…

This is an early-stage study testing a new type of CAR-T cell therapy called CT1190B. It aims to see if this treatment is safe and effective for adults with B-cell non-Hodgkin lymphoma that has come back or hasn't responded to standard treatments. The study will also look at how …

This study is testing a new method to detect breast cancer using a simple blood test. Researchers want to see if this new test is accurate and reliable for finding cancer signals. The trial is recruiting 100 healthy volunteers to help validate the test's performance.

This study is testing a new type of MRI scan to check the health of transplanted kidneys without needles, contrast dye, or invasive biopsies. It aims to create a personalized 'baseline' for each kidney by scanning donors before donation, allowing for more sensitive, early detecti…

This study is developing and testing an artificial intelligence (AI) tool designed to help doctors diagnose brain diseases from MRI scans. It will use brain scan data from 1,000 patients with conditions like tumors, stroke, or Alzheimer's to see if the AI can match or improve dia…

This study is testing whether a new type of MRI scan can accurately assess fatty liver disease without needing a painful liver biopsy. Researchers will enroll 500 patients to see if the scan's measurements match the results from biopsies, which is the current best test. The goal …

This study is testing a new artificial intelligence (AI) tool designed to predict which patients are at high risk of their colorectal cancer spreading to the liver after curative surgery. The tool analyzes patients' routine CT scans, pathology images, and clinical data. The goal …

This study is testing if getting a flu shot can help prevent serious heart problems in people who recently had a heart attack or similar event. Researchers will give about 6,600 participants either a real flu shot or a placebo (dummy shot) and then track their health for a year. …

This study is looking at whether a numbing injection near the spine, given during chest surgery, helps reduce serious problems afterward like lung infections and breathing failure. Researchers will observe 500 patients having minimally invasive chest surgery, checking their pain,…

This study aims to find out which of two common anesthesia drugs causes fewer breathing problems during and after tonsil surgery in children. Researchers will compare remimazolam and ciprofol in 114 children aged 2-12. The goal is to improve safety and recovery for kids undergoin…

This study looks back at the medical records of 12 people with Familial Mediterranean Fever (FMF) to see how well different medications worked for them in real life. Researchers are not testing new treatments but are observing what happened when patients took existing drugs. The …

This study is testing a new artificial intelligence (AI) tool designed to predict if and how a patient's early-stage liver cancer might return after surgery. Researchers will follow 353 patients for two years after their operation to see if the AI's predictions about high-risk re…

This study aims to discover biological markers in blood and other samples that could help identify people at high risk for stroke before it happens. Researchers will follow 7,000 participants—both stroke patients and healthy individuals—for up to four years, tracking their health…

This study aims to find out if spinal anesthesia or general anesthesia leads to fewer lung problems after hip fracture surgery in older adults. It will enroll 40 patients aged 65+ whose surgery is delayed more than 48 hours. Researchers will compare oxygen levels, lung function, …

This study aims to create an artificial intelligence (AI) tool that can predict which colorectal cancer patients are at high risk of the cancer spreading to their liver after curative surgery. Researchers will develop the tool by analyzing existing medical records, CT scans, and …

This study aims to understand how the laxative used to clean the bowel before a colonoscopy affects the community of bacteria living in the gut, especially in people who have had their gallbladder removed. Researchers will compare 10 people who have had gallbladder surgery with 1…

This is a large, long-term observational study that aims to collect detailed information from 50,000 people with headaches over 10 years. The goal is to better understand the different causes and patterns of headaches by tracking patients' symptoms, treatments, and health data. R…

This study aims to understand if anxiety or depression (emotional distress) affects how well immunotherapy works for people with liver cancer. It will follow 651 patients receiving standard immunotherapy to see if their mental health influences how long the treatment keeps the ca…