AI predicts liver cancer return, guides personalized drug cocktail

NCT ID NCT07282184

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is for people with early-stage liver cancer who are scheduled for surgery. Researchers are testing whether an artificial intelligence (AI) tool can predict each patient's risk of the cancer returning. Patients identified as high-risk will receive a combination of chemotherapy, targeted therapy, and immunotherapy before and after surgery. The goal is to see if this personalized plan improves the chance of staying cancer-free for two years compared to surgery alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Combination of chemotherapy (HAIC with mFOLFOX6), oral Lenvatinib, and a PD-1 inhibitor

What this could lead to

If successful, this approach could offer a personalized treatment plan that significantly lowers the chance of liver cancer returning after surgery.

What could go wrong

This is an early-phase trial with only 144 participants, so results may not apply to everyone. The drug combination can cause serious side effects, and the AI tool's predictions may not always be accurate.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tongji Hospital

    RECRUITING

    Wuhan, Hubei, 438700, China

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••