Virus therapy takes on bladder cancer in early trial

NCT ID NCT07359235

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a modified virus called KD01, given directly into the bladder, to see if it is safe and can fight bladder cancer. The study includes 29 patients with either high-risk non-muscle-invasive bladder cancer or muscle-invasive bladder cancer. Some patients also receive an immunotherapy drug called AK104. The goal is to find the right dose and check for side effects and tumor response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

KD01 (a modified virus that targets and kills cancer cells) and AK104 (an immunotherapy drug) in some patients

What this could lead to

If successful, this could point toward a new treatment option for bladder cancer that uses a virus to attack tumors directly.

What could go wrong

This is a very early Phase 1 trial with only 29 participants, so safety and effectiveness are not yet proven. The virus may cause side effects or fail to shrink tumors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

infiltrating bladder urothelial carcinoma non-invasive bladder urothelial carcinoma urinary bladder carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430074, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact