New registry study tests antibody drugs for rare nerve disease
NCT ID NCT06885957
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This registry study is tracking 200 people with a rare autoimmune disease called neuromyelitis optica spectrum disorder (NMOSD) who are positive for the AQP4 antibody. Researchers are evaluating how well monoclonal antibody therapies work in real-world settings, focusing on preventing relapses and slowing disability. The study will also look at brain scans and immune markers over time to better understand treatment effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- monoclonal antibody therapy
- What this could lead to
- If successful, this study could confirm that monoclonal antibody therapies effectively reduce relapse rates and disability progression in people with NMOSD.
- What could go wrong
- This is an observational registry, not a controlled trial, so results may be influenced by other factors. The study is also limited to a Chinese population, so findings may not apply globally.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, 430030, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Massive Real-World study to track brain and nerve autoimmune disorders