Tongji Hospital

This study is testing a new combination treatment for people with advanced liver cancer (hepatocellular carcinoma) who also have high blood pressure in their liver (portal hypertension) due to cirrhosis. The treatment combines a minimally invasive procedure (TACE) with three drug…

This study is testing a new oral medication called ivarmacitinib for people with moderate-to-severe rheumatoid arthritis (RA) who haven't gotten enough relief from common first-line drugs like methotrexate. It aims to see if this pill can better control the disease and reduce sym…

This early-phase study is testing a new cell therapy called AZD0120 in adults with end-stage kidney disease who are waiting for a transplant but have high levels of antibodies that make finding a compatible donor very difficult. The goal is to see if this therapy can safely reduc…

This early-phase study is testing a new type of cell therapy for adults with acute myeloid leukemia (AML) that has come back or hasn't responded to other treatments. The therapy involves modifying a patient's own immune cells to recognize and attack two specific markers found on …

This study aims to find the best combination treatment for advanced liver cancer that cannot be removed by surgery. It will compare two different local drug delivery methods (TACE and HAIC), each combined with two other cancer drugs, in about 364 patients. The main goal is to see…

This study is testing if a smartwatch with artificial intelligence (AI) can help people recover after a heart attack. It will see if the watch, worn for 3 months during rehab, can better monitor health, improve quality of life, and reduce return trips to the hospital compared to …

This early-stage study is testing a new cell therapy called ACE1831 for people with severe systemic lupus erythematosus (SLE) that has not improved with standard treatments. ACE1831 is made from immune cells (gamma delta T cells) donated by healthy people. The main goals are to s…

This early-phase study is testing a new type of CAR-T cell therapy designed to attack two common targets (CD19 and CD22) on cancer cells. It aims to see if this approach is safe and effective for adults with B-cell acute lymphoblastic leukemia or non-Hodgkin lymphoma that has com…

This study aims to find out if the diabetes medication glimepiride can help people who have both type 2 diabetes and chronic heart failure. It will involve about 1,500 participants who will be randomly assigned to receive either glimepiride or a placebo (a dummy pill) for three y…

This study is testing if a combination of two drugs—lenvatinib (a targeted therapy) and a PD-1 inhibitor (an immunotherapy)—can help control advanced solid tumors that have a specific genetic feature called '11q13 amplification.' It will involve about 60 adults with various advan…

This study aims to see if an artificial intelligence (AI) model can better identify which liver cancer patients need immunotherapy after surgery to prevent the cancer from coming back. It will follow 300 patients who have had their liver tumors surgically removed. The AI will ana…

This study aims to see if an oral medicine made from bezoar, a traditional ingredient, can help people recover from a brain bleed (intracerebral hemorrhage), a severe type of stroke. Researchers will give the medicine to 300 adults who recently had a small to moderate brain bleed…

This study is testing a combination of targeted drugs and radiation to treat an aggressive form of bladder cancer. The goal is to control the cancer while avoiding surgical removal of the bladder. It is for patients with a specific cancer marker called HER2-positive.

This study is testing a new blood test to see if it can accurately tell when liver cancer comes back after a patient's initial treatment. Researchers will enroll 162 adults who have had or will have treatment like surgery or ablation. They will compare the results of this new tes…

This study is testing a new AI tool designed to help doctors tell the difference between common, harmless uterine fibroids and a rare but dangerous cancer called uterine sarcoma. The tool analyzes MRI scans to predict which fibroids might turn cancerous. Researchers will enroll 5…

This study is testing a new blood test that detects tiny amounts of leftover cancer cells after liver cancer surgery. Researchers want to see if this test can better predict which patients' cancer will return and identify who might benefit from additional immunotherapy treatment.…

This study is testing a new method to manage pain after lung surgery. It combines a nerve-block injection near the ribs with a patient-controlled pain medication pump. The goal is to provide better pain relief with fewer side effects like nausea, helping patients recover more com…

This study aims to see how well a pain medication called osellidine works for women having outpatient hysteroscopy surgery. Researchers will observe and compare osellidine to standard pain treatments, focusing on pain control, side effects, and how quickly patients recover. The g…

This study is testing if a virtual reality (VR) mindfulness program can help patients feel less anxious and experience less pain during minor vascular surgeries done with local anesthesia. Researchers will enroll 160 patients, with half using the VR program and half receiving sta…

This study looks back at 600 patients who had short ear, nose, and throat surgeries. It compares two different target levels for how deeply asleep patients were kept during the procedure. The goal is to see which level leads to a smoother, higher-quality recovery when patients wa…

This early-stage study is testing a new Chinese herbal formula called TJAOA103 to see if it can safely relieve common and bothersome symptoms of menopause, such as vaginal dryness, pain, and urinary problems. About 113 women aged 45-70 will take the herbal pills twice daily for 4…

This study aims to test and improve a computer model designed to predict how uterine fibroids affect a woman's chances of getting pregnant. It will follow over 7,000 women with fibroids who want to conceive, tracking their pregnancy outcomes. The goal is to create a reliable tool…

This study looks back at medical records to see if eating a low-carbohydrate diet is linked to better survival for women with a specific type of ovarian cancer who are on a standard maintenance therapy. Researchers will compare the outcomes of about 600 patients who had different…

This study aims to observe and understand how a group of related autoimmune diseases that attack the brain, nerves, and muscles progress over time in real-world patients. It will follow 1,550 adults diagnosed with conditions like multiple sclerosis, myasthenia gravis, and autoimm…