New study aims to prevent bone fractures in liver cancer patients
NCT ID NCT07537972
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study looks at whether starting denosumab early, along with a standard immunotherapy, can prevent bone problems like fractures or spinal cord compression in people with liver cancer that has spread to the bones. About 50 adults with liver cancer and bone metastases will be randomly assigned to get either early denosumab plus immunotherapy or immunotherapy alone with rescue treatment only if needed. The goal is to see which approach better delays bone complications and improves quality of life.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, 430030, China
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