New drug duo targets hard-to-treat cancers with rare genetic marker

NCT ID NCT07417501

First seen Feb 22, 2026 · Last updated May 23, 2026 · Updated 16 times

Summary

This study tests whether combining lenvatinib (a targeted therapy) with a PD-1 inhibitor (immunotherapy) can shrink or slow advanced solid tumors that have a specific genetic change called 11q13 amplification. About 60 adults with various cancers (like esophageal, head and neck, breast, lung, or liver) will receive the same treatment. Researchers will track tumor response and side effects to see if this approach is effective and safe.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tongji Hospital

    Wuhan, Hubei, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.