Mind over tumor? new study probes if depression blunts immunotherapy in liver cancer

NCT ID NCT07325565

Recruiting now Knowledge-focused Sponsor: Tongji Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether emotional disorders like depression and anxiety affect how well immunotherapy works in people with liver cancer. Researchers will follow 651 patients and compare treatment outcomes between those with and without emotional distress. The goal is to understand the mind-body connection in cancer care, not to test a new drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could show that screening for emotional disorders helps predict who will benefit from immunotherapy, leading to better personalized care.
What could go wrong: This is an observational study, not a treatment trial. It may find no clear link, or results may not apply to all liver cancer patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma intrahepatic cholangiocarcinoma liver cancer Liver Neoplasms mental disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EMOTIONAL DISORDER LIVER CANCER

Contacts and locations

Locations

Division of Hepato-Pancreato-Biliary Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, 430000, China

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