New sedative ciprofol aims to cut heart injury after lung surgery

NCT ID NCT07028593

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether ciprofol, a newer sedative, can reduce heart injury after lung surgery compared to the standard drug propofol. About 1,058 adults aged 45–80 having video-assisted lung surgery will be randomly assigned to receive one of the two drugs during anesthesia. The main goal is to see if ciprofol lowers the rate of heart muscle damage in the days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ciprofol (also known as HSK3486)

What this could lead to

If ciprofol works better than propofol, it could become a safer sedative for surgery, lowering the risk of heart damage after lung operations.

What could go wrong

This is a Phase 4 trial, but it only looks at one type of surgery and one complication. Results may not apply to other surgeries or patients, and ciprofol might not prove superior.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm mediastinal cancer Thoracic Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tongji hospital

    RECRUITING

    Wuhan, China

    Contact

    Contact