New cocktail of drugs shows promise for tough bile duct cancer

NCT ID NCT07392541

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new combination of four drugs—two standard chemotherapies plus an immunotherapy and a cholesterol drug—in people with advanced bile duct cancer. All 29 participants will receive the same treatment. Researchers will check how many patients see their tumors shrink and how long the cancer stays under control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

adebrelimab (an immunotherapy drug), gemcitabine, cisplatin, and simvastatin

What this could lead to

If this works, it could offer a new treatment option that shrinks tumors and delays cancer growth in people with advanced bile duct cancer.

What could go wrong

This is an early, small exploratory study with only 29 participants. The combination may cause significant side effects, and it is not yet known if it works better than standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bile duct adenocarcinoma biliary tract cancer extrahepatic bile duct carcinoma gallbladder cancer intrahepatic cholangiocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tongji Hospital

    RECRUITING

    Wuhan, Hubei, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••