Fred Hutchinson Cancer Center

This study tests whether a faster dose increase of the drug sonrotoclax, given with other medicines, is safe for people with certain blood cancers (CLL, SLL, or mantle cell lymphoma). The cancers may be new, returned, or not responding to treatment. The goal is to see if this qui…

This early-phase trial tests a personalized cell therapy for people with metastatic solid tumors that carry a specific genetic mutation (KRAS G12V). Patients' own immune cells are genetically modified to recognize and attack cancer cells. The study aims to find the safest dose an…

This study is for people with certain blood cancers, like leukemia or lymphoma. It tests a stem cell transplant from a half-matched donor, using a special drug combo (treosulfan and fludarabine) plus low-dose radiation to prepare the body. The goal is to see if this approach help…

This study tests whether reducing the dose of the drug linvoseltamab after an initial good response can keep multiple myeloma under control while causing fewer side effects. About 30 adults with myeloma that has returned or stopped responding to other treatments will take part. R…

This study tests a radioactive antibody (211At-BC8-B10) given before a donor stem cell transplant for people with high-risk acute leukemias or myelodysplastic syndrome. The antibody seeks out and delivers radiation to cancer cells while sparing healthy cells. The goal is to find …

This study tests whether a dental cleaning shortly after a stem cell transplant can prevent chronic graft-versus-host disease (GVHD), a serious condition where donor cells attack the patient's body. About 45 adults receiving a stem cell transplant for blood cancer will get a post…

This study looks at whether adding fiber supplements to the diet is possible for patients receiving donor stem cell transplants for blood cancers. The goal is to see if fiber can improve nutrition, support healthy gut bacteria, and help the gut work better after treatment. About …

This study aims to create simple screening tools to identify financial hardship in people with Alzheimer's disease and their caregivers. Researchers will interview patients and caregivers, then survey large groups to develop and test these measures. The goal is to help doctors an…

This study looks at how to help people in Zimbabwe who have both cancer and HIV stay engaged in their HIV care while they are being treated for cancer. Researchers will first observe 150 patients to understand the barriers, then develop and test strategies to overcome them with a…