New chemo cocktail before transplant aims to stop blood cancer from coming back

NCT ID NCT06928662

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 23 times

Summary

This study tests a new treatment sequence for adults with aggressive blood cancers (like AML, MDS, or CMML) that are likely to return after standard therapy. Participants receive a combination of chemotherapy drugs (decitabine plus FLAG-Ida) followed by low-dose radiation and a donor stem cell transplant. The goal is to see if this approach is safe and helps keep the cancer away longer. About 36 people will take part in this early-phase trial.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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