New combo attack on tough blood cancers: chemo plus transplant shows promise

This study tests a new approach for adults with aggressive blood cancers (like AML) that are likely to return after standard treatment. Participants receive a combination of chemotherapy drugs (decitabine plus FLAG-Ida) and low-dose radiation, followed immediately by a stem cell transplant from a healthy donor. The goal is to safely kill cancer cells and help the body produce new, healthy blood cells, reducing the chance of relapse. About 36 people will take part to find the best dose and check safety.