New combo therapy aims to beat back tough blood cancers

NCT ID NCT04375631

First seen Mar 16, 2026 · Last updated May 01, 2026 · Updated 7 times

Summary

This study is for adults with certain blood cancers (like acute myeloid leukemia) that have come back or not responded to standard treatment. Participants receive a strong chemotherapy combination (CLAG-M or FLAG-Ida) followed immediately by a stem cell transplant from a donor. The goal is to find the safest dose of total body irradiation given before the transplant to kill cancer cells and help the new stem cells take hold. After transplant, drugs are given to reduce the risk of graft-versus-host disease, a common complication where donor cells attack the patient's body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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