Engineered immune cells take aim at stubborn leukemia

NCT ID NCT07583303

First seen May 18, 2026 · Last updated May 25, 2026 · Updated 1 time

Summary

This early-phase study tests a new treatment called BSB-2002 for adults with a specific type of acute myeloid leukemia (AML) that has returned or not responded to standard therapy. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack cancer cells carrying the NPM1 mutation. Before receiving the modified cells, patients get two chemotherapy drugs to prepare their body. The main goal is to find the safest dose and see if the therapy can help control the disease.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.