Supercharged immune cells take aim at Hard-to-Treat cancers
NCT ID NCT06043713
First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times
Summary
This early-phase trial tests a personalized treatment for people with metastatic solid tumors that have a specific genetic change called KRAS G12V. The patient's own immune cells (T cells) are collected, genetically modified to recognize and attack cancer cells carrying the KRAS G12V protein, and then infused back. The study aims to find the safest dose and check for side effects in up to 24 participants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for METASTATIC MALIGNANT SOLID NEOPLASM are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Fred Hutch/University of Washington Cancer Consortium
RECRUITINGSeattle, Washington, 98109, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a tracer that hunts unstable iron light up hidden tumors?
- Vaccine trains immune system to hunt down cancer cells
- Gut radiation may revive immunotherapy in resistant cancers
- One shot: could a single radiation dose control metastatic cancer?
- Can talking about stress ease Cancer's mental toll? new study aims to find out
- Mayo clinic hunts for hidden cancer clues in DNA and proteins