PREGNANCY

This study tests whether eating a balanced meal made from local foods once a day during pregnancy can help women in rural Pakistan handle heat stress better and have healthier babies. About 292 women will either eat this meal daily or continue their usual diet. Researchers will m…

This study looks at whether structured nutrition counseling can improve diet quality and reduce harmful compounds called advanced glycation end products in pregnant women with gestational diabetes. About 48 first-time pregnant women, aged 18-35, will be assigned to either receive…

This study tests a new program that teaches pregnant women in Bangladesh how to care for their teeth and gums during routine prenatal visits. Over 95% of pregnant women in Bangladesh have gum disease, but oral health is not part of standard pregnancy care. The study will compare …

This study will test if digital tools like reminders can help pregnant women in Lombok, Indonesia, take their daily multiple micronutrient supplements (MMS) more consistently. About 10,012 women will be split into four groups to compare digital support versus standard care, and b…

This study looks at whether giving extra progesterone injections for 6 weeks after a positive pregnancy test can improve live birth rates in women aged 18-37 who have low progesterone levels after a fresh embryo transfer. Half of the 214 participants will receive the extra proges…

This study looks at two different approaches to help pregnant people with gum disease get better dental care. Participants will receive free dental check-ups, cleanings, and supplies. The goal is to see which method reduces gum inflammation and improves oral health habits, and wh…

This study will test a smart insulin pump (MiniMed 780G) with continuous glucose monitoring in 20 pregnant women with type 2 diabetes. The goal is to keep blood sugar in a safe range for pregnancy and improve health outcomes for both mother and baby. Participants will be followed…

This study will check if a simple finger prick blood test gives the same pregnancy hormone (beta-hCG) results as a standard blood draw from a vein. Researchers will compare both methods in 40 pregnant women. If finger stick blood works just as well, it could make pregnancy testin…

This study checks if a new home pregnancy test (Clara Multi-Level) gives the same results whether used by a person at home or a trained professional. About 180 women will take the test at the study center and answer questions about using it. The goal is to make sure the test is e…

This study tests different combinations of an online program called CARRII to help Native women reduce their risk of alcohol-exposed pregnancy. 512 women who drink alcohol and are at risk for pregnancy will use the program for 3 months. The goal is to find the most effective and …

This study tests a counseling program called Healthy Families-PrEP that helps women in rural Uganda use HIV prevention medicine (PrEP) when trying to get pregnant, during pregnancy, and after giving birth. About 660 women who are HIV-negative but at risk will take part. The goal …

This study will compare how well women stick to taking a single daily pill that prevents both HIV and pregnancy versus taking two separate pills. About 300 women without HIV will try both methods in a crossover design. The goal is to see if a combined pill makes it easier to stay…

This study tests whether teaching women about healthy eating, activity, and other lifestyle habits before or during early pregnancy can improve their heart health and lower the chance of problems like gestational diabetes and preeclampsia. Two hundred women at risk for these comp…

This study tests a personalized support program (PTBCARE+) for pregnant individuals at high risk of delivering early. The program includes stress reduction tools, a website/app, and other resources. Researchers will compare stress levels and birth outcomes between those who recei…

This study looks at whether using a weighted blanket can reduce nighttime leg cramps, improve sleep quality, and lower anxiety and stress in pregnant women. Fifty women in their third trimester will use the blanket for 14 days and compare results to a 14-day period without it. Th…

This study tests whether using a breast pump for nipple stimulation can safely start labor in pregnant women. The gentle suction may trigger the body's own oxytocin to encourage contractions. Researchers will measure total labor time and compare it to standard methods. The goal i…

This study looks at whether a mindfulness-based stress reduction program can help first-time pregnant women feel less anxious, worry less about their baby's health, and improve their overall mental well-being. About 100 women between 12 and 28 weeks of pregnancy will take part. T…

This study aims to see if using a standard method for cervical ripening (preparing the cervix for labor) increases the chance of a vaginal delivery. Researchers will compare two approaches: one using a balloon catheter alone, and another combining the catheter with a medication c…

This study tests a mindfulness-based psychoeducation program for pregnant women who are very afraid of childbirth. The program includes group sessions twice a week for 4 weeks, teaching relaxation and coping skills. Researchers will measure fear levels, self-perception, and spiri…

This study compares two ways to manage pain after a planned C-section: a small dose of morphine given with the spinal anesthesia, versus a nerve block (TAP block) using numbing medicine. One hundred women will be randomly assigned to one of the two groups. The goal is to see whic…

This study tests whether a new type of absorbable staple can close the skin faster and leave a better-looking scar than traditional stitches in women having a C-section. About 237 women will take part, and their scars will be evaluated from photos taken 5-10 days and 4-6 weeks af…

This study looks at whether pregnant people with type 1 or type 2 diabetes can safely keep using their insulin pump during labor instead of switching to IV insulin. About 30 participants will use their own pump under a hospital safety plan, and their results will be compared to p…

This study will test whether virtual doula services can improve birth outcomes and satisfaction for first-time mothers living in rural areas. Researchers will enroll 614 pregnant women across the U.S. and randomly assign them to receive virtual doula support or standard care. The…

This study compares using an injection port versus single-use needles for giving insulin to pregnant women with diabetes. The goal is to see if the port helps women stick to their insulin schedule and feel more satisfied with their care. About 44 participants will try both method…

This study looks at whether eating milk chocolate during labor can shorten the pushing stage (second stage) for pregnant women. Researchers will compare 180 healthy women who eat chocolate to those who don't. The goal is to see if the extra energy helps make labor faster and easi…

This study tests an online program called STORK that helps couples expecting their first baby manage changes in their sexual relationship. About 268 couples will take part, starting during pregnancy and continuing until 12 months after birth. The program provides information and …

This study tests a 4-week virtual reality (VR) program designed to help first-time pregnant women feel more confident and less anxious about giving birth. Sixty-eight women will be randomly assigned to use the VR tool or receive standard care. The goal is to see if VR can improve…

This study tests whether a 10% lidocaine spray can reduce the pain of inserting an IV needle in women scheduled for a C-section. About 150 participants will receive either the spray or a placebo before IV insertion and rate their pain on a 0–10 scale. The goal is to see if the sp…

This study tests whether a weekly exercise program, plus extra pelvic floor therapy if needed, can reduce pelvic girdle pain in pregnant women. About 40 women with pelvic pain will be randomly assigned to either the exercise program or standard care. The goal is to see if this ap…

This study tests if short weekly mindfulness exercises delivered through a mobile app can help first-time parents manage stress and emotions during pregnancy. Expecting mothers and fathers in Singapore will use the app, wear a Fitbit, and complete surveys about their well-being a…

This study tests a structured education program for first-time pregnant women to reduce fear of childbirth and stress, and to strengthen their belief in normal birth. About 72 women in their third trimester will either receive the program or standard prenatal care. The goal is to…

This study tests whether AI-assisted ultrasound devices can help frontline health workers in rural Ethiopia detect pregnancy problems early. About 1,059 pregnant women will be split into three groups: two using different AI ultrasound tools and one receiving standard care without…

This study looks at a natural chemical called kynurenine in the blood of pregnant women. Some women have chronic kidney disease, which raises their risk of a dangerous pregnancy complication called preeclampsia. Researchers want to see if kynurenine levels differ between women wi…

This study will test better ways to screen for tuberculosis (TB) in pregnant and postpartum women in Guinea-Bissau. Researchers will use a symptom checklist, stool tests, and AI-powered chest X-rays to find more TB cases. The goal is to improve health for mothers and babies and g…

This study looks at how doctors trust artificial intelligence (AI) when estimating a baby's weight during pregnancy. About 308 clinicians will review ultrasound cases and compare AI estimates with traditional methods. Some doctors will see extra info about the AI's accuracy, whil…

This study follows 376 pregnant women from 36 weeks of pregnancy to 12 weeks after birth. Researchers will measure hip, back, belly, and pelvic floor muscles to see if they are linked to how the baby is delivered (vaginal or C-section) and if women have pelvic floor problems afte…

This study looks at whether teaching first-time mothers how to do perineal massage during pregnancy can help them feel more in control, confident about a normal birth, and less afraid of childbirth. About 152 pregnant women in Turkey will either get this special education plus re…

This study tests whether a brief educational session about safe exercise during pregnancy can improve women's knowledge, confidence, and physical activity levels. Thirty pregnant women with low-risk pregnancies will be randomly assigned to receive either standard prenatal care or…

This study will test whether a mobile app called MI MOM can improve pregnancy and postpartum health for 500 pregnant women on Medicaid. One group uses the app and gets text messages with health tips, videos, and optional support from a community health worker. The other group rec…

This study tests a simple tool—short information cards on a mobile phone—to help pregnant people feel more confident when deciding about prenatal genetic screening. About 1,400 participants will use the cards before their first doctor visit, or receive usual care. Researchers wil…

This study looks at whether a video call (teleconsultation) works as well as an in-person visit for checking pregnant patients before they receive anesthesia during delivery. About 250 first-time mothers will take part, and researchers will compare how complete and accurate the i…

This study looks at whether training obstetric providers to counsel pregnant patients about workplace accommodations can improve outcomes. About 400 pregnant patients and their providers will take part. The goal is to see if this training leads to better job protection, fairer wa…

This study looks at how physical activity changes during pregnancy in women with type 1 or type 2 diabetes. Researchers will track activity levels, blood sugar, and emotional well-being in 175 pregnant women. The goal is to understand what support these women need to stay active …

This study looks at how cystic fibrosis medications (CFTR modulators) change in the body during pregnancy and after childbirth in 30 women. Researchers will measure drug levels in blood, breast milk, and umbilical cord blood. The goal is to understand how these drugs work in preg…

This study tests a smartphone app called Womb Watch that uses the phone's microphone to listen to fetal movements, like kicks and hiccups. Researchers will enroll 60 pregnant women (both low- and high-risk) to see if the app is easy to use and accurate. The goal is to provide a s…

This study looks at how daily routines like sleep, activity, and meal timing in early pregnancy relate to blood sugar patterns and the risk of gestational diabetes. About 140 pregnant women without diabetes will wear monitors and use a food app to track their habits. The goal is …

This study will collect ultrasound images from 50 pregnant people between 18 and 28 weeks of pregnancy. The goal is to use these images to train artificial intelligence (AI) to automatically measure key parts of the baby, like head size and leg length. The results will help get t…

This study looks at how often pregnant women who have their water break early carry antibiotic-resistant bacteria. Researchers will collect samples from 250 women across French hospitals to track these bacteria and identify risk factors. The goal is to help doctors choose better …

This study looks at how body image dissatisfaction, eating behaviors, and daily stress relate to blood sugar levels in pregnant women. Researchers will monitor 50 women between 14 and 28 weeks of pregnancy using a continuous glucose monitor and daily surveys over 10 days. The goa…

This study tests whether special educational sessions can help first-time mothers breastfeed exclusively. 160 pregnant women will either attend four weekly classes on breastfeeding skills and confidence or receive standard care. Researchers will check how many are still exclusive…

This study follows 1,000 pregnant women and their partners in the UK from early pregnancy to about two months after birth. Researchers want to learn how their health information needs change over time and what makes it hard to get the right information. Participants fill out shor…

This observational study follows 111 women with multiple sclerosis who received rituximab (or similar CD-20 antibodies) before or during pregnancy, and their infants. Researchers will measure the baby's B-cell levels, infection rates, and vaccine responses during the first year o…

This study follows 120 women with twin pregnancies and their 240 babies for one year after birth. Researchers will measure air pollution, diet, lifestyle, and chemical exposures to see how these factors affect growth and health. No treatments or drugs are given—only observation a…

This study looks at whether binaural beats—a type of sound therapy—can lower the amount of anxiety medication (midazolam) needed during a C-section done with spinal anesthesia. About 200 pregnant women will be randomly assigned to listen to binaural beats or a placebo sound. The …

This observational study will test if a noninvasive finger monitor can predict how well pregnant women, including those with severe preeclampsia, respond to fluids. Researchers will compare the finger device's readings to standard heart ultrasound results during a leg-raising tes…

This study tests a short video where Black women share their labor pain experiences. Doctors who watch it may become more empathetic, which could help build trust with their Black patients. About 120 people, including doctors and new mothers, will take part. The goal is to improv…

This study works with people who have Primary Ciliary Dyskinesia (PCD) and healthcare professionals to create easy-to-understand resources about fertility and pregnancy safety. The goal is to develop a patient guide and a toolkit for doctors, based on what patients and providers …