POST TRAUMATIC STRESS DISORDER

This small study tested whether transcranial magnetic stimulation (TMS) can lower blood pressure and ease PTSD symptoms in women aged 18-44 who have both conditions. Four participants received 30 TMS sessions over 6 weeks. Researchers measured changes in 24-hour blood pressure an…

This study followed 44 people with PTSD who had already completed a prior methylone (TSND-201) trial. Over 52 weeks, researchers checked their symptoms and safety each month. If PTSD symptoms returned, participants could receive more methylone treatment. The goal was to see if th…

This pilot study tested a new type of brain stimulation, called accelerated intermittent theta burst stimulation (aiTBS), for people with anxiety disorders or PTSD. Fifteen participants received the non-invasive treatment targeting a novel brain area. The study measured changes i…

This study tested whether monthly 45-minute psychological interviews over 6 months could reduce post-traumatic stress symptoms in cancer patients affected by the COVID-19 pandemic. It included 29 adults with solid tumors who had moderate to high PTSD symptoms. The goal was to see…

This study looked at whether a web-based program called webSTAIR, which teaches skills to manage emotions and relationships, is feasible and helpful for people with PTSD who are on a waitlist for behavioral health treatment. Seventy adults from a hospital clinic in Boston took pa…

This study looked at whether giving a special therapy called EMDR to people in the emergency room right after a traumatic event could help prevent post-traumatic stress disorder (PTSD). About 110 adults who were at high risk for PTSD took part. The therapy uses eye movements to h…

This study looked at whether adding a type of talk therapy called prolonged exposure therapy (PET) to standard opioid addiction treatment can help reduce PTSD symptoms. 82 adults with both opioid use disorder and PTSD took part. Some got only addiction treatment, while others als…

This study tested a type of group therapy called Resilience-Oriented Therapy (RoT) for adults in Rwanda who were struggling with mental health issues like trauma, depression, anxiety, or anger. 427 people took part, and the therapy was tailored to each person's main problem, such…

This study tested whether transcranial magnetic stimulation (TMS), a noninvasive treatment that uses magnetic fields to stimulate brain regions, can improve PTSD symptoms and related brain activity. Fifty adults with partial PTSD received either active TMS or a sham procedure ove…

This study tested three ways to deliver Acceptance and Commitment Therapy (ACT) for adults aged 20-40 with mild to moderate PTSD in Pakistan. Participants were split into three groups: standard clinic therapy, clinic therapy with a supporting web app, and fully online therapy wit…

This study tested a program called MOSAIC Plus for pregnant women and mothers of children under 5 who have experienced intimate partner violence and have symptoms of depression or PTSD. The program pairs women with community advocates who provide support and teach skills to impro…

This study tested whether interpersonal psychotherapy (IPT) works as well as two established treatments for chronic post-traumatic stress disorder (PTSD): prolonged exposure therapy and relaxation therapy. 110 adults with chronic PTSD took part, receiving weekly sessions over 14 …

This study looked at whether adding lofexidine to standard buprenorphine treatment can improve symptoms of both PTSD and opioid use disorder in veterans. 84 veterans on stable buprenorphine therapy were enrolled. The goal was to see if the combination reduced opioid use and PTSD …

This study looked at whether mindfulness training could help veterans with PTSD who struggle with anger and aggression. 61 veterans took part. The goal was to see if learning to focus on the present moment could help them control angry feelings and reduce aggressive behavior.

This study tested whether methylone, a substance similar to MDMA, can safely reduce PTSD symptoms in adults. 79 participants with moderate to severe PTSD received either methylone or a placebo once a week for four weeks, then were followed for six more weeks. The goal was to see …

This study tested a program called EMPOWER for veterans who completed trauma-focused therapy for PTSD and saw improvement. The program includes a workbook and four therapist check-ins over 12 weeks to help veterans manage symptoms on their own. Researchers wanted to see if it cou…

This study tested whether a simple technique called progressive muscle relaxation training can reduce symptoms of post-traumatic stress disorder (PTSD) in people affected by the February 6 Kahramanmaraş earthquake. 44 adults with PTSD took part. The training involves tensing and …

This study tested a 5-week online group program called Rare Group Problem Management Plus (PM+) for parents of children with rare diseases. The program teaches stress management and problem-solving skills to help reduce anxiety, depression, and distress. Eight parents participate…

This study tested whether a probiotic called Lactobacillus rhamnosus GG can reduce inflammation and PTSD symptoms in veterans. Researchers enrolled 383 veterans with PTSD and gut issues, giving them either the probiotic or a placebo. The goal was to see if calming inflammation in…

This study looked at whether 6 months of supervised exercise training could reduce PTSD symptoms and improve physical health in older veterans with PTSD. 80 veterans took part, with one group doing exercise and another receiving health education. The goal was to see if exercise c…

This study tested whether a three-week aerobic exercise program could reduce PTSD symptoms and improve sleep in 82 adults who survived the February 2023 earthquake in Turkey. Participants were randomly assigned to either supervised exercise sessions or a control group. Researcher…

This study tested whether a simple writing therapy, done over video calls, could help prevent or reduce PTSD in women who recently experienced sexual assault. Thirty women who visited a Sexual Assault Nurse Examiner (SANE) clinic within 7 days of the assault took part. The therap…

This study tested two online courses designed to help paramedics in Singapore manage stress, anxiety, depression, and burnout during the COVID-19 pandemic. 63 paramedics took part, completing six weekly online modules. The goal was to see which course better improved mental healt…

This study tested whether a single dose of the antibiotic minocycline, given before guided memory recall, could reduce the strength of intrusive memories in people with PTSD or cocaine use disorder. 138 participants took either minocycline or a placebo and then imagined a persona…

This study tested a modified version of Goal Management Training, called Trauma-Informed Goal Management Training (TI-GMT), in 33 adults with PTSD. The program teaches mindfulness and goal-setting skills over nine weekly online sessions. Researchers measured changes in PTSD sympt…

This study tested a type of talk therapy called Acceptance and Commitment Therapy (ACT) to help veterans with PTSD improve their social support and relationships. 107 veterans took part, and the therapy focused on helping them feel less isolated and more connected to family and f…

This study tested a new way of delivering care for people with anxiety and depression in Danish general practices. 302 adults with conditions like panic disorder, social anxiety, or PTSD took part. The model involved a team of doctors, nurses, and therapists working together, and…

This study tested whether adding a social support program to standard therapy helps trauma-affected refugees with PTSD. 196 unemployed refugees received either standard treatment or standard treatment plus collaboration with municipal social services. The goal was to improve dail…

This study tested whether a smartphone app that retrains attention can help people with post-traumatic stress disorder (PTSD). Over 1,300 adults with PTSD symptoms used one of four app versions for two weeks. Researchers measured changes in PTSD symptoms right after training and …

This study tested whether a mild electrical brain stimulation technique called tDCS could improve the results of trauma-focused therapy for people with PTSD. 63 adults with chronic PTSD received either real tDCS or a fake version during therapy sessions. The goal was to see if th…

This study tested a short virtual reality program called SHINE-VR for 6 adolescents aged 12-17 who had experienced sexual abuse and felt trauma-related shame. The program included three VR sessions focused on psychoeducation and sharing feelings in a virtual group. Researchers me…

This study tested a drug called methylone in 62 adults with severe PTSD. Participants took methylone capsules once a week for 3 to 4 weeks. Researchers measured changes in PTSD and depression symptoms to see if the drug is safe and helpful.

This study tested a workshop called STEP-Home for 221 post-9/11 Veterans who had trouble reintegrating into civilian life. The workshop taught skills like emotional control, problem solving, and attention to improve daily function and reduce anger. It was designed as a non-stigma…

This study tested a one-day life skills workshop for veterans with mild traumatic brain injury, chronic pain, and mental health conditions like PTSD and depression. The workshop taught coping strategies to reduce distress and improve reintegration into civilian life. 176 veterans…

This study tested whether Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) can reduce PTSD and depression symptoms in children aged 8 to 19 when delivered in schools. It also tested a strategy to help school clinicians adopt and stick with the therapy. The trial involved 292 …

This study tested a mobile app called BounceBack Now, designed to help people manage trauma-related mental health issues like PTSD, depression, and anxiety. Researchers worked with 29 adults in primary care, including many from underserved groups, to see if the app was easy to us…

This study tested whether Written Exposure Therapy, a treatment where people write about their traumatic experiences, can work when delivered virtually in a group setting. The participants were 29 military and police personnel with PTSD. The goal was to see if this approach is ac…

This pilot study tested the Safe and Sound Protocol (SSP), a device that plays filtered music through an app to stimulate the vagus nerve, in 45 therapy clients with PTSD and anxiety. Participants used the SSP alongside their regular therapy and completed questionnaires about the…

This study tested a 16-week parenting program called KEEP for foster and kinship parents. The goal was to reduce depression, anxiety, PTSD, and behavior problems in foster youth aged 4 to 21. Researchers focused on underserved and rural communities in Oregon. The program teaches …

This study tested whether a type of talk therapy called Cognitive Processing Therapy (CPT) can help adults who experienced the 2023 earthquakes in Turkey. Thirty-six participants with PTSD symptoms were randomly assigned to receive CPT or usual care. The goal was to see if CPT re…

This study tested a 10-session art therapy program for adults with trauma-related symptoms who have difficulty with traditional talk therapy. 38 participants made artwork to process memories and emotions. Researchers measured changes in emotional expression, self-esteem, and resi…

This study looked at whether teaching military members to train service dogs can improve symptoms of PTSD, anxiety, depression, and concussion. 156 participants spent one hour twice a week working with professional dog trainers. Researchers measured changes in stress, mood, sleep…

This study tested whether a racecar-simulation program combined with psychological skills training could help veterans with PTSD improve their ability to handle stress and emotions. One veteran completed the program, which included techniques like self-talk, goal-setting, and bio…

This study tested a coaching program for doctors to improve communication with Black and Latinx families during hospital rounds. The program taught doctors to be more respectful, collaborative, and trauma-aware. Researchers measured whether families felt more trust and satisfacti…

This study examines how often patients and their relatives develop post-traumatic stress disorder (PTSD) after a sudden cardiac arrest. Researchers interviewed 45 people (20 survivors and 20 relatives) within a week of the event and again at 3 months using standard questionnaires…

This study looked at how people with PTSD pay attention to their surroundings. Researchers used a change blindness test to see if patients are quicker to notice changes, especially emotional ones. 80 adults with PTSD and healthy controls participated. The goal was to understand t…

This study looked at how mindfulness-based cognitive therapy (MBCT) changes brain activity in 61 adults with PTSD. Participants received either MBCT or a mind-body comparison therapy, and researchers used fMRI scans to measure brain connectivity before and after treatment. The go…

This study looked at how negative emotions and stress influence alcohol use in 81 women veterans, including those with PTSD. Researchers measured cravings, heart rate, and drinking patterns, and also examined how these effects change across the menstrual cycle. The goal was to be…

This study followed survivors of the 2015 Paris terrorist attacks for up to 6 years, using brain scans to see how trauma affects the brain's ability to control unwanted memories. Researchers compared 216 survivors with people who were not exposed to the attacks. The goal was to u…

This study used MRI and PET scans to examine the glutamate system in people with major depression, PTSD, or bipolar disorder. Researchers aimed to understand how a specific glutamate receptor (mGluR5) relates to these conditions. 180 participants aged 18-70 completed cognitive te…

This study aimed to find factors that can predict whether someone will develop post-traumatic stress disorder (PTSD) after a traumatic event like a serious injury or violence. Researchers followed 460 adults who came to the emergency room within a month of trauma and were at mode…

This study looked at how people with post-traumatic stress disorder (PTSD) predict their emotional reactions to future events. Researchers compared 97 participants with and without PTSD to see if those with PTSD tend to expect more intense negative emotions than they actually exp…

This study looked at how the COVID-19 pandemic impacted the mental health of 501 nursing home workers in Occitanie, France. Researchers measured rates of post-traumatic stress disorder (PTSD), depression, and burnout using standard questionnaires. The goal was to understand how c…

This study looked at the specific symptoms of complex post-traumatic stress disorder (PTSD) compared to regular PTSD. Researchers used questionnaires to measure dissociation, emotional control, and trauma in 300 adults. The goal was to better understand and identify complex PTSD,…

This study looked at whether a special planning tool, called a POST form, helps older adults (65+) get the medical care they prefer at the end of life. Researchers worked with 389 people, including those with dementia, to see if their treatment matched their wishes. The goal was …

This study tested whether a smartphone app could help veterans with serious mental illnesses like schizophrenia and bipolar disorder track their own symptoms. 87 veterans used the app to monitor their activity, sleep, and social interactions. The goal was to see if this data coul…

This study created and tested a mobile app called VetEd for student veterans dealing with mental health issues like depression, PTSD, or anxiety. The goal was to help them manage academics, mental health, and find resources. Researchers worked with 13 veterans to see if the app w…

This study looked at how a single dose of dronabinol (a synthetic cannabinoid) affects fear-related brain activity in people with PTSD, trauma-exposed individuals without PTSD, and healthy controls. Using brain scans, researchers measured how the drug influences fear extinction c…

This study followed 14 people who called a crisis hotline after terror attacks in Paris, London, Barcelona, and Strasbourg. Researchers asked them to rate how their symptoms changed over time. The goal was to understand what kind of help they needed.

This early-stage trial tested the safety and drug levels of methylone in 40 healthy volunteers aged 25 to 55. Participants received a single oral dose of methylone or a placebo. The study measured how the drug moves through the body and checked for side effects. This is a first s…