POST-TRAUMATIC STRESS DISORDER

This study tests whether a trauma-informed program called Strength at Home works better than the usual state-approved program to reduce intimate partner violence. About 800 men who are court-ordered to attend such programs, along with their partners, will take part. Researchers w…

This study explores whether artificial intelligence (AI) can accurately identify mental health conditions like ADHD, autism, depression, and anxiety by analyzing a person's speech patterns. Researchers will collect speech samples from 500 people aged 16-60 who are being evaluated…

This pilot study tests whether a non-invasive brain stimulation technique called rTMS can reduce alcohol cravings in veterans who also have mild traumatic brain injury or PTSD. Twenty veterans will receive either real or placebo rTMS over 10 sessions in 2 weeks. The goal is to se…

This study tests whether a non-invasive brain stimulation technique called TMS can lower blood pressure and reduce PTSD symptoms in women aged 18-44 who have both conditions. Thirty participants will receive TMS and have their blood pressure monitored for 24 hours. The goal is to…

This study tests a brief form of therapy called Brief Prolonged Exposure (Brief PE) to see if it can reduce posttraumatic stress in people who have had a spinal cord injury. About 200 adults in inpatient rehab will either get this therapy or standard care. The goal is to ease PTS…

This study aimed to see if propranolol, a blood pressure medicine, could reduce PTSD symptoms in teenagers by interfering with the way traumatic memories are re-stored in the brain. It planned to enroll 12- to 18-year-olds with PTSD for at least three months. However, the study w…

This early-stage study tests whether psilocybin, the active ingredient in magic mushrooms, can safely reduce PTSD symptoms in 20 adults who are already on antidepressant medication. Participants receive psilocybin in a controlled setting, and some also get trauma-focused talk the…

This study tests whether a mobile neurofeedback program can help new mothers who have experienced trauma feel less stressed, anxious, and depressed. About 40 mothers with PTSD symptoms and babies aged 3-9 months will use the app for 12 weeks. Researchers will check if it improves…

This study looks at whether unlicensed professionals can provide cognitive behavioral therapy (CBT) to people with conditions like anxiety, depression, OCD, and PTSD. About 250 participants will receive therapy at Massachusetts General Hospital. The goal is to see if their mental…

This study tests a therapy called Deep Brain Reorienting (DBR) for people with post-traumatic stress disorder (PTSD). 234 adults will be randomly assigned to receive DBR or join a waitlist. The goal is to see if DBR reduces PTSD symptoms like distress and flashbacks.

This study compares a new, shorter therapy for PTSD to the usual longer treatments. About 82 adults with PTSD or subthreshold PTSD will take part. The goal is to see if the brief approach reduces symptoms just as well, helping more people get effective care faster.

This study tests whether a stellate ganglion block—a numbing injection near the neck—can safely and quickly reduce PTSD symptoms in veterans. About 410 veterans with chronic PTSD who have tried other treatments will receive either the real injection or a sham (fake) one. Research…

This study tests a program called MOSAIC Plus, which pairs pregnant women and mothers of young children who have experienced intimate partner violence with trained advocates. The program aims to reduce symptoms of depression and post-traumatic stress, and help prevent further vio…

This study tests a web-based program called webSTAIR for people with PTSD who are waiting for treatment. The goal is to see if it's easy to use, helpful, and can reduce PTSD symptoms. About 70 adults from a Boston clinic will take part, using a computer or phone to learn skills f…

This study tests whether a nerve block injection in the neck can reduce PTSD symptoms. 79 adults with PTSD will receive either an anesthetic or a placebo (saline) injection. Researchers will measure changes in stress responses and brain activity using scans and questionnaires. Th…

This study looks at whether a brain training method called neurofeedback can help new mothers who have experienced trauma feel better and manage their emotions. Twenty moms with PTSD or dissociation symptoms, who are 3-24 months postpartum, will try the training alongside their u…

This study was designed to see if a program called Primary Care Intervention for PTSD (PCIP) could help teenagers with post-traumatic stress disorder. Researchers planned to compare the program to usual care and test if it could be delivered via telehealth. However, the study was…