Nerve block shot could ease PTSD in veterans, large trial underway

NCT ID NCT05169190

First seen Oct 31, 2025 · Last updated May 13, 2026 · Updated 34 times

Summary

This study tests whether a stellate ganglion block—a numbing injection near the neck—can safely and quickly reduce PTSD symptoms in veterans. About 410 veterans with chronic PTSD who have tried other treatments will receive either the real injection or a sham (fake) one. Researchers will measure symptom changes and side effects to see if this fast-acting approach works.

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Contacts and locations

Locations

  • James A. Haley Veterans' Hospital, Tampa, FL

    Tampa, Florida, 33612, United States

  • Minneapolis VA Health Care System, Minneapolis, MN

    Minneapolis, Minnesota, 55417-2309, United States

  • VA Long Beach Healthcare System, Long Beach, CA

    Long Beach, California, 90822, United States

  • VA Salt Lake City Health Care System, Salt Lake City, UT

    Salt Lake City, Utah, 84148-0001, United States

  • White River Junction VA Medical Center, White River Junction, VT

    White River Junction, Vermont, 05001-3833, United States

  • William S. Middleton Memorial Veterans Hospital, Madison, WI

    Madison, Wisconsin, 53705-2254, United States

Conditions

Explore the condition pages connected to this study.