Magic mushroom compound shows promise for PTSD in early trial

NCT ID NCT06407635

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 30 times

Summary

This early-stage study tests whether psilocybin, the active ingredient in magic mushrooms, can safely help adults with chronic PTSD who are already on antidepressants. Twenty participants will receive psilocybin therapy, with some also getting trauma-focused talk therapy. The goal is to see if psilocybin can reduce PTSD symptoms and improve well-being, while checking for side effects.

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Contacts and locations

Locations

  • Johns Hopkins Center for Psychedelic and Consciousness Research

    Baltimore, Maryland, 21224, United States

Conditions

Explore the condition pages connected to this study.