PTSD memory eraser trial for teens pulled before it began

NCT ID NCT04921982

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study aimed to see if the blood pressure drug propranolol could reduce PTSD symptoms in adolescents by blocking the reconsolidation of traumatic memories. Participants would have taken propranolol or a placebo before briefly recalling their trauma, once a week for six weeks. However, the trial was withdrawn before enrolling any teens, so no data was collected.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Propranolol

What this could lead to

If it had worked, this could have pointed toward a new way to treat PTSD in teens by weakening traumatic memories.

What could go wrong

The trial was withdrawn before any participants were enrolled, so no results are available. Even if it had run, it was a small early-phase study, and propranolol's effect on memory is still uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AP-HP Louis Mourier

    Colombes, France

  • CH Bohars

    Bohars, France

  • CH Guillaume Régnier

    Rennes, 35000, France

  • CH Le Havre

    Le Havre, France

  • CHU Angers

    Angers, France

  • CHU Besançon

    Besançon, France

  • CHU Limoges

    Limoges, France

  • CHU Nantes

    Nantes, France

  • CHU Poitiers

    Poitiers, France

  • CHU Rouen

    Rouen, France