PTSD memory eraser trial for teens pulled before it began

NCT ID NCT04921982

Terminated Disease control Sponsor: Rennes University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study aimed to see if the blood pressure drug propranolol could reduce PTSD symptoms in adolescents by blocking the reconsolidation of traumatic memories. Participants would have taken propranolol or a placebo before briefly recalling their trauma, once a week for six weeks. However, the trial was withdrawn before enrolling any teens, so no data was collected.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Propranolol
What this could lead to: If it had worked, this could have pointed toward a new way to treat PTSD in teens by weakening traumatic memories.
What could go wrong: The trial was withdrawn before any participants were enrolled, so no results are available. Even if it had run, it was a small early-phase study, and propranolol's effect on memory is still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST-TRAUMATIC STRESS DISORDER

Contacts and locations

Locations

AP-HP Louis Mourier

Colombes, France
CH Bohars

Bohars, France
CH Guillaume Régnier

Rennes, 35000, France
CH Le Havre

Le Havre, France
CHU Angers

Angers, France
CHU Besançon

Besançon, France
CHU Limoges

Limoges, France
CHU Nantes

Nantes, France
CHU Poitiers

Poitiers, France
CHU Rouen

Rouen, France

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