Rennes University Hospital

This study tests whether giving a protein called albumin after a liver transplant can lower the chance of acute kidney injury. About 400 adults receiving a new liver will be split into two groups: one gets albumin to keep levels above 30 g/L for five days, the other only gets it …

This study compares two drugs, rituximab and ocrelizumab, for people with relapsing-remitting multiple sclerosis (MS). The goal is to see if rituximab works as well as ocrelizumab at preventing MS attacks and new brain lesions over two years. About 386 adults aged 18-55 with acti…

This early-stage study tests whether repeated injections of stem cells from donated fat tissue are safe for people with primary progressive multiple sclerosis (MS), a form that steadily worsens. Ten adults aged 18–55 with moderate disability will receive the cells directly into t…

This study tests whether early brain-training feedback (EEG neurofeedback) can help people recover arm movement after a stroke. About 40 adults who had a stroke within the past 3 weeks will receive either real or fake (sham) neurofeedback along with standard rehabilitation. The g…

This study tests a type of hypnotherapy called E2R for people with chronic insomnia (trouble sleeping for months). About 136 adults will either get E2R hypnotherapy or usual care (like sleep medications). The goal is to see if hypnosis can reduce insomnia severity without the sid…

This study compares two types of keyhole surgery for early-stage womb cancer: robot-assisted and standard laparoscopy. About 1,680 women will be randomly assigned to one method to see which is more cost-effective and leads to better recovery and quality of life. The goal is to he…

This study tests a new, non-invasive MRI technique to detect early brain changes linked to Alzheimer's disease in 50 adults aged 50-80 with mild memory concerns. Researchers will compare brain scans of participants with healthy controls to see if this method can identify those at…

This study aims to understand why about 20% of children with B-acute lymphoblastic leukemia (B-ALL) relapse after treatment. Researchers will analyze bone and blood samples from 50 newly diagnosed children at three critical points during therapy. They focus on a protein called CD…

This study looks at whether patients who take antiplatelet drugs (blood thinners) and have a minor head injury, but no other signs of brain bleeding, still need a CT scan. Current guidelines say they do, but this may not be necessary. Researchers will follow 3,200 adults to see i…

This study tests a new set of rules for treating neck injuries in conscious, stable patients before they reach the hospital. The goal is to see if these rules can reduce unnecessary neck immobilization and imaging, and improve how patients are routed through the healthcare system…

This study looks at whether two substances in urine (TIMP-2 and MMP-2) can predict kidney damage in people with spina bifida. Researchers will compare these biomarkers with standard tests that measure bladder and kidney function. If successful, it could lead to a simpler, non-inv…

This study looks at whether temporarily taking away the team leader's vision during a medical emergency simulation helps the team perform better. The leader relies on verbal communication from the team instead of seeing the situation. Researchers will measure teamwork and clinica…

This study is testing whether a new, low-cost brain scan can find early signs of Alzheimer's and Parkinson's disease. Researchers will compare brain scans from 120 people, including those at risk for Alzheimer's, those with Parkinson's, and healthy volunteers. The goal is to deve…