Rennes University Hospital

This study tests whether using a blood marker called transferrin saturation to guide bloodletting (removing blood) improves quality of life in people with HFE haemochromatosis, a genetic condition causing iron buildup. 239 adults already on maintenance bloodletting will be random…

This study looks at whether people over 50 with a stable, inactive form of secondary progressive multiple sclerosis can stop taking their disease-modifying drugs without getting worse. Researchers will track 250 participants for 2 years to see if stopping treatment leads to more …

This study aimed to see if the blood pressure drug propranolol could reduce PTSD symptoms in adolescents by blocking the reconsolidation of traumatic memories. Participants would have taken propranolol or a placebo before briefly recalling their trauma, once a week for six weeks.…

This study was designed to test whether transplanting a person's own fat cells into healed bedsores could stop the sores from returning. It planned to enroll adults with paralysis who had a healed pelvic bedsore for at least 6 months. However, the study was withdrawn before any p…

This study explores how anxiety contributes to treatment-resistant depression. Researchers will follow 37 adults with depression to see if anxiety levels can predict who will have a harder time recovering. The goal is to better identify at-risk patients and develop more targeted …

This study was designed to see if X-rays taken before knee replacement surgery could reliably show ligament damage in people with knee arthritis. It was an observational study, meaning no treatment was given. However, the study was withdrawn before enrolling any participants, so …

This study investigates whether a specific mouthwash (buccotherm) helps maintain a balanced and healthy community of bacteria in the mouth, compared to a placebo mouthwash. Healthy adults with at least 20 natural teeth will use the mouthwash twice daily for 14 weeks. Researchers …

This study planned to check how often the adrenal glands stop working properly after chemotherapy in adults with blood cancers. It aimed to measure cortisol levels after a stimulation test. However, the study was withdrawn before any participants were enrolled, so no results are …

This study follows 20 adults with hereditary transthyretin amyloidosis (ATTRv) who have both nerve and heart involvement. They are treated with patisiran or vutrisiran for two years. Researchers use MRI scans and questionnaires to see how the drugs affect heart structure and func…