Could a simple mouthwash keep your Mouth's bacteria healthy?
NCT ID NCT04973358
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study investigates whether a specific mouthwash (buccotherm) helps maintain a balanced and healthy community of bacteria in the mouth, compared to a placebo mouthwash. Healthy adults with at least 20 natural teeth will use the mouthwash twice daily for 14 weeks. Researchers will use advanced DNA sequencing to track changes in the types and diversity of oral bacteria, aiming to see if the mouthwash supports a healthy microbiome rather than disrupting it.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- buccotherm mouthwash
- What this could lead to
- If successful, this could show that certain mouthwashes support a healthy oral microbiome, potentially reducing risks of cavities, gum disease, and other health issues linked to oral bacteria.
- What could go wrong
- This is an early-stage study with a small number of participants. The mouthwash may not meaningfully change the microbiome compared to placebo, and any benefits for disease prevention remain speculative.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BUCCAL MICROBIOTA are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Rennes
Rennes, France