Heart mystery: do Nerve-Targeting drugs also protect the heart?
NCT ID NCT05873868
First seen Jan 05, 2026 · Last updated May 11, 2026 · Updated 19 times
Summary
This study looks at 20 adults with hereditary transthyretin amyloidosis (a rare disease causing protein buildup in nerves and heart) who are already taking patisiran or vutrisiran for nerve symptoms. Researchers want to see if these drugs also affect heart structure and function over 24 months using MRI scans and a heart-related quality-of-life questionnaire. The goal is to better understand the heart effects, not to test a new treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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APHP Henri Mondor
Créteil, France
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CHU Bordeaux Haut-Levêque
Bordeaux, France
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CHU Grenoble Alpes
Grenoble, France
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CHU Nancy Institut Louis Mathieu
Nancy, France
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CHU Rangueil Toulouse
Toulouse, France
Conditions
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