MS drug holiday for Over-50s: safe or risky?

NCT ID NCT03653273

Ongoing Disease control Sponsor: Rennes University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether people over 50 with a stable, inactive form of secondary progressive multiple sclerosis can stop taking their disease-modifying drugs without getting worse. Researchers will track 250 participants for 2 years to see if stopping treatment leads to more disability or relapses, and whether it improves quality of life and reduces costs.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis secondary progressive multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE SCLEROSIS

Contacts and locations

Locations

AP-HM

Marseille, France
AP-HP (La Pitié Salpêtrière)

Paris, France
CH Poissy

Poissy, France
CH Quimper

Quimper, France
CH de Chartres

Chartres, France
CH de Foch

Suresnes, France
CH de Libourne

Libourne, France
CHU Angers

Angers, France
CHU Brest

Brest, France
CHU Clermont-Ferrand

Clermont-Ferrand, France
CHU Dijon

Dijon, France
CHU Grenoble

Grenoble, France
CHU Lille

Lille, France
CHU Montpellier

Montpellier, France
CHU Nancy

Nancy, France
CHU Nantes

Nantes, France
CHU Nice

Nice, France
CHU Poitiers

Poitiers, France
CHU Rennes

Rennes, France
CHU Strasbourg

Strasbourg, France
CHU Tours

Tours, France
CHU de Bordeaux

Bordeaux, France
CHU de Nîmes

Nîmes, France
Fondation de Rothschild

Paris, France
Hospices Civils Lyon

Lyon, France
Hôpital Henri Mondor

Créteil, France
Hôpital Saint Vincent de Paul

Lille, France

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