Could a sleep drug soothe PTSD? new study recruits troops and civilians

NCT ID NCT05948540

Terminated Symptom relief Sponsor: Global Coalition for Adaptive Research Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests whether daridorexant, a drug used for insomnia, can reduce PTSD symptoms in 200 adults, including active-duty service members, veterans, and civilians. Participants receive either the drug or a placebo for 12 weeks, and researchers track changes in PTSD severity and safety. The goal is to find a new way to ease the burden of PTSD.

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST-TRAUMATIC STRESS DISORDER

Contacts and locations

Locations

Advanced Discovery Research

Atlanta, Georgia, 30318, United States
Alexander T. Augusta Military Medical Center (ATAMMC):

Fort Belvoir, Virginia, 22060-5285, United States
Cincinnati Veteran's Affairs Medical Center

Fort Thomas, Kentucky, 41075, United States
Homestead Associates in Research, Inc.

Miami, Florida, 33032, United States
Madigan Army Medical Center

Joint Base Lewis McChord, Washington, 98433, United States
Tripler Army Medical Center (TAMC)

Tripler AMC, Hawaii, 96859, United States
Upstate Clinical Research Associates, LLC

Williamsville, New York, 14221, United States
Walter Reed National Military Medical Center (WRNMC)

Bethesda, Maryland, 20889-5632, United States
Wilford Hall Ambulatory Surgical Center (WHASC)

San Antonio, Texas, 78236, United States

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