Global Coalition For Adaptive Research

This study is testing whether a medication called daridorexant, which is currently used for insomnia, can help control symptoms of Post-Traumatic Stress Disorder (PTSD). It will involve 200 active-duty service members and veterans. Participants will be randomly assigned to receiv…

This study aims to find new medications to help control PTSD symptoms in active-duty military and veterans. It will test up to five different drugs against a placebo in about 800 participants over 12 weeks. The trial uses a flexible design that allows researchers to adjust which …

This study aims to find out if the medication fluoxetine is safe and effective at reducing symptoms of Post-Traumatic Stress Disorder (PTSD). It will involve 200 active-duty service members and veterans who have PTSD. Participants will be randomly assigned to receive either fluox…

This large international trial is testing several different treatments for glioblastoma (GBM), a fast-growing brain cancer. It aims to find which therapies work best for newly diagnosed patients and for those whose cancer has returned. The trial uses a smart, flexible design to q…