DIABETES MELLITUS

This study aims to see if advanced scans of the eyes and brain can help doctors better spot and treat a type of nerve and blood vessel damage linked to diabetes. Researchers will also test whether a traditional Chinese herbal medicine called Tangshen'an Granule is safe and effect…

This study aims to see if a specific type of dental filling material works as well for people with well-controlled diabetes as it does for people without diabetes. Researchers will place fillings in 56 adults and check how well they stay in place, look, and feel over 18 months. T…

This study aims to see how well the Omnipod 5 automated insulin pump system works for people with Type 1 diabetes in their daily lives. It will follow about 150 patients, including children and adults, for one year to measure blood sugar control, quality of life, and safety. The …

This study is testing if a pill called DLBS1033, when added to standard care, can help control nerve damage in people with diabetic neuropathy. It will enroll 34 adults with type 2 diabetes and nerve pain to see if the treatment reduces inflammation, helps nerves heal, and improv…

This study is testing whether using a continuous glucose monitor (a small sensor that tracks blood sugar levels every few minutes) can help people who have both type 2 diabetes and heart failure. Researchers want to see if better, real-time sugar monitoring during and after a hos…

This study aims to see if a new topical ointment called GM-XANTHO can help heal pressure ulcers (bedsores) more effectively than standard care alone. It will involve 58 adult patients with stage 2 or 3 pressure ulcers, including many with diabetes. Participants will apply either …

This study is testing if a custom-made, soft toe divider can help people with diabetes who have had a small toe amputated. The goal is to see if the divider improves how they walk, redistributes pressure on the foot, and reduces the risk of developing new foot ulcers. This is a s…

This early-stage study is testing whether insulin-producing cells grown from stem cells in a lab can help people with diabetes. Researchers will transplant these cells into 30 adults who have had diabetes for over 5 years and require insulin. The main goals are to see if the trea…

This study aims to help people with diabetes in rural Kentucky by connecting clinics with community resources. It will test whether providing patient navigators and support for needs like food and housing improves diabetes control and quality of life. The program will involve 12,…

This study is testing whether a supervised, community-based exercise program can help older adults with multiple chronic conditions improve their health and quality of life. It will enroll 150 people aged 50 and older who have at least two conditions like heart disease risk, diab…

This study tests whether continuous glucose monitors (CGMs) help low-income, uninsured, or Medicaid patients with type 2 diabetes better manage their blood sugar. Fifty participants will be randomly assigned to either use a CGM for six months or continue with traditional finger-p…

This study is testing a new computer-based decision tool designed to help doctors better protect cancer survivors from heart problems. The tool will be tested with 60 cancer survivors who are at risk for heart disease. Researchers want to see if the tool is easy for doctors and p…

This VA program aims to help clinics better provide proven health services for women Veterans in midlife. It will test two different support strategies across at least 18 VA facilities to help them offer trauma-informed care, menopause symptom therapy, and weight management progr…

This study tests whether a new care coordination program helps cancer patients better manage chronic conditions like high blood pressure, diabetes, and high cholesterol during cancer treatment. Researchers will compare patients who receive the new program to those getting usual c…

This study is testing a new support package for older adults who have two or more long-term health problems, like high blood pressure, diabetes, or arthritis. The package includes digital tools, personalized guidance, and ongoing support to help manage their health. Researchers w…

This study aims to develop a new screening tool for heart and related diseases. Researchers will use a smartphone-compatible device to record a simple, 1-minute heart rhythm reading from 5,000 participants. They will then use artificial intelligence to see if patterns in this rea…

This study is testing if a low-cost thermal camera works as well as a professional one for spotting early foot problems in people with diabetes. It will involve 130 participants who will have their feet scanned with both cameras. The goal is to see if the cheaper camera can relia…

This study aims to find the best way to measure hard foot calluses, especially in people with diabetes who are at risk for serious foot sores. Researchers will compare four different painless scanning tools on 50 adults with and without diabetes who have foot calluses. The goal i…

This study is testing whether a non-drug therapy called acupressure can help manage blood sugar levels and reduce feelings of anxiety in older adults living with diabetes. Researchers will compare real acupressure, fake acupressure, and standard care in 48 participants to see if …

This study aims to find out if having a root canal done in one appointment causes more or less pain afterwards than splitting the treatment into two visits, specifically for patients with diabetes. Researchers will randomly assign 200 diabetic patients needing a root canal to eit…

This study aims to identify which non-vascular factors—like nerve damage, poor blood sugar control, or nutrition—make diabetic foot ulcers worse or more likely to come back. It will observe 100 adults with diabetes and existing foot ulcers for one year, tracking wound size, heali…

This study aims to understand how gum tissue heals after a common dental procedure in people with diabetes compared to those without. Researchers will enroll 40 adults with receding gums to see if healing speed, gum coverage, and related biological factors differ between the two …

This is an early safety study to see how two slightly different versions of an experimental injection for diabetes are absorbed by the body. It will involve 60 healthy volunteers to measure drug levels in the blood and check for any side effects. The main goal is to gather basic …

This study aims to understand if diabetes affects how well a specific type of pain-blocking injection (an ankle block) works for patients having foot or ankle surgery. Researchers will observe and compare 46 patients—some with diabetes and some without—to see how quickly the pain…

This study aims to understand how the fear of dangerously low blood sugar (hypoglycemia) affects whether people with diabetes stick to their diet and take their medications correctly. Researchers will survey 100 adults with diabetes who have experienced a low blood sugar event be…

This study aims to understand if standard pre-surgery fasting rules work the same for people with diabetes. Researchers will use ultrasound to measure stomach volume in 220 adults with and without diabetes who are scheduled for elective surgery. The goal is to see if diabetes, wh…

This study aims to understand how common severe emotional distress is among adults living with type 2 diabetes at a hospital in Nice, France. Researchers will ask 246 participants to fill out questionnaires about their feelings and quality of life related to diabetes. The goal is…

This study aims to understand if a person's long-term blood sugar levels (measured by HbA1c) are linked to how slowly their stomach empties before surgery. Researchers will use a bedside ultrasound scan on 134 adults having elective surgery to measure stomach contents after fasti…

This study aims to understand the relationship between urinary function (like bladder control and flow) and the development of other common age-related health problems, such as diabetes, heart disease, and high blood pressure. It will follow 500 Beijing residents aged 60 and olde…