Could a single pill replace two for diabetes?

NCT ID NCT07538466

Not yet recruiting Knowledge-focused Sponsor: Addpharma Inc. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early-stage trial will test a new tablet called AD-123 in 50 healthy adults. Researchers want to see if taking one AD-123 pill works similarly to taking two separate pills (AD-1231 and AD-1232) together. The study focuses on safety and how the drug moves through the body, not on treating diabetes itself.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: AD-123 (oral tablet) and combination of AD-1231 and AD-1232 (oral tablets)
What this could lead to: If successful, this study could show that a single tablet (AD-123) works as well as taking two separate tablets, potentially simplifying diabetes treatment.
What could go wrong: This is a very early Phase 1 trial in only 50 healthy volunteers, not people with diabetes. It only measures safety and drug levels, not whether the drug actually helps control diabetes.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES MELLITUS

Contacts and locations

Locations

H Plus Yangji Hospita

Seoul, South Korea

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