DEXMEDETOMIDINE
Clinical trials for DEXMEDETOMIDINE explained in plain language.
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New hope in brain surgery: drug may prevent dangerous complications
Disease control CompletedThis study tested if giving a sedative drug called dexmedetomidine during a specific brain surgery could help patients. The surgery was for a life-threatening brain bleed caused by a burst aneurysm. Researchers wanted to see if the drug could reduce dangerous blood vessel spasms …
Matched conditions: DEXMEDETOMIDINE
Phase: NA • Sponsor: Tanta University • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Common surgery drug could be key to longer life for elderly cancer patients
Disease control CompletedThis study tested whether adding a medication called dexmedetomidine to standard pain control after cancer surgery could help older patients live longer. Researchers enrolled 1,500 patients aged 65+ who had surgery to remove a solid tumor. They wanted to see if this drug, by redu…
Matched conditions: DEXMEDETOMIDINE
Phase: NA • Sponsor: Peking University First Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New anesthesia combo aims to protect nerves during spine operations
Disease control CompletedThis study compared two different anesthesia combinations used during major spine surgery. The goal was to see which method better preserves the electrical signals doctors use to monitor nerve and spinal cord function during the operation, helping to prevent nerve damage. It invo…
Matched conditions: DEXMEDETOMIDINE
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New drug combo could protect brains during surgery
Disease control CompletedThis study tested whether adding the drug dexmedetomidine to standard mannitol treatment better controls brain pressure during prostate surgery. Researchers enrolled 60 patients undergoing elective robotic prostate surgery to compare the two approaches. They measured pressure cha…
Matched conditions: DEXMEDETOMIDINE
Phase: PHASE2, PHASE3 • Sponsor: Cairo University • Aim: Disease control
Last updated Mar 23, 2026 15:29 UTC
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Safer sedation sought for risky blood pressure procedure
Disease control CompletedThis study looked back at 142 patients who had a procedure to calm overactive nerves near the kidneys to treat hard-to-control high blood pressure. It compared two different sedation (sleepiness-inducing) drug combinations used during the procedure to see which one led to fewer s…
Matched conditions: DEXMEDETOMIDINE
Sponsor: Ebru Girgin Dinc • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Nighttime drug combo tested to help critically ill patients sleep better
Symptom relief CompletedThis study tested whether giving a combination of two low-dose sedative drugs at night could improve sleep quality for patients in the intensive care unit (ICU) who need help breathing. Researchers enrolled 174 patients aged 50 or older who were on a ventilator or high-flow oxyge…
Matched conditions: DEXMEDETOMIDINE
Phase: PHASE4 • Sponsor: Peking University First Hospital • Aim: Symptom relief
Last updated Apr 02, 2026 03:26 UTC
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Sedative tested to shield elderly lungs in cancer surgery
Symptom relief CompletedThis study tested whether a sedative drug called dexmedetomidine could help protect the lungs of older adults during laparoscopic surgery for colorectal cancer. The goal was to see if giving the drug during surgery could improve breathing and reduce lung complications afterward. …
Matched conditions: DEXMEDETOMIDINE
Phase: NA • Sponsor: The Second Affiliated Hospital of Chongqing Medical University • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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New approach tested to ease pain after C-Section
Symptom relief CompletedThis study tested whether adding a medication called dexmedetomidine to a standard pain-blocking injection could improve pain relief after a planned cesarean section. It involved 80 women who had C-sections with spinal anesthesia. Researchers compared pain levels, how soon women …
Matched conditions: DEXMEDETOMIDINE
Phase: PHASE1 • Sponsor: Majid Fakhir Mutar Alhamaaidah • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Gentler sedation tested for Kids' heart repair
Symptom relief CompletedThis study compared two ways to keep children comfortable and stable during a procedure to close a hole in the heart. It tested whether a lighter sedation method works as well as general anesthesia for 3-8 year olds. Researchers measured heart rate, blood pressure, recovery time,…
Matched conditions: DEXMEDETOMIDINE
Phase: NA • Sponsor: Tanta University • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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New hope for easing pain after mastectomy
Symptom relief CompletedThis study compared two different drugs given through an IV during surgery to see which one better manages pain in the first two days after a mastectomy. It involved 40 women undergoing breast cancer surgery. Researchers measured how long before patients needed extra pain medicin…
Matched conditions: DEXMEDETOMIDINE
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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Sedative may speed up stomach after surgery, curbing nausea
Symptom relief CompletedThis study tested whether a sedative drug called dexmedetomidine helps the stomach empty faster after keyhole gallbladder removal surgery. Researchers used ultrasound scans to measure stomach volume in 80 patients before and after their operation. The goal was to see if this drug…
Matched conditions: DEXMEDETOMIDINE
Phase: NA • Sponsor: Tanta University • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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New approach aims to stop Post-Surgery confusion in elderly cancer patients
Symptom relief CompletedThis large study tested whether adding a medication called dexmedetomidine to standard pain control could reduce the risk of delirium (sudden, severe confusion) in older adults recovering from cancer surgery. Researchers enrolled 1,500 patients aged 65 and older who were having m…
Matched conditions: DEXMEDETOMIDINE
Phase: NA • Sponsor: Peking University First Hospital • Aim: Symptom relief
Last updated Mar 23, 2026 15:18 UTC
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Breathing calm: inhaled sedative tested to protect hearts during obesity surgery
Symptom relief CompletedThis study tested whether giving patients a calming medication as a mist to breathe in before surgery could help protect their hearts. It involved 90 adults with severe obesity undergoing weight-loss surgery. Researchers wanted to see if this approach safely reduced dangerous spi…
Matched conditions: DEXMEDETOMIDINE
Phase: NA • Sponsor: Tanta University • Aim: Symptom relief
Last updated Mar 20, 2026 14:48 UTC
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Common mineral beats drug for surgery pain relief
Symptom relief CompletedThis study compared two medications given during surgery to help control pain afterwards. It involved 93 adults having bladder tumor removal under spinal anesthesia. Patients received either magnesium sulfate, dexmedetomidine, or a saline solution during their operation. The magn…
Matched conditions: DEXMEDETOMIDINE
Phase: NA • Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital • Aim: Symptom relief
Last updated Mar 18, 2026 14:41 UTC
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Finding the best spinal dose for longer pain relief after C-Section
Symptom relief CompletedThis study aimed to find the better dose of a medication called dexmedetomidine when added to standard spinal anesthesia for planned cesarean sections. It involved 60 women having planned C-sections to see if a 5-microgram or 10-microgram dose provided longer-lasting pain relief …
Matched conditions: DEXMEDETOMIDINE
Phase: PHASE4 • Sponsor: Bahria International Hospital • Aim: Symptom relief
Last updated Mar 12, 2026 13:51 UTC
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Do common anesthesia drugs shield your blood vessels during surgery?
Knowledge-focused CompletedThis study aimed to see if the anesthesia drug dexmedetomidine helps protect the delicate lining of blood vessels during surgery. Researchers measured specific markers in the blood of 90 healthy adults undergoing nose surgery to check for vessel damage. The goal was to gather kno…
Matched conditions: DEXMEDETOMIDINE
Phase: PHASE4 • Sponsor: Firat University • Aim: Knowledge-focused
Last updated Mar 11, 2026 14:54 UTC