DEXMEDETOMIDINE

This study looked at whether giving a medicine called dexmedetomidine during a procedure to fix a brain aneurysm can lower the chance of blood vessels tightening dangerously afterward. The trial involved 90 adults with a type of brain bleed. Researchers measured how much the arte…

This study tested whether adding dexmedetomidine to the standard drug mannitol can better control increased pressure inside the skull during robot-assisted prostate surgery. Sixty adults at low surgical risk took part. The main goal was to measure changes in the optic nerve sheat…

This study looked at whether adding dexmedetomidine to standard pain relief after cancer surgery helps elderly patients (65-90 years old) live longer. The idea is that this medicine might reduce stress, inflammation, and confusion, which could improve immune function and lower th…

This study tested whether giving a low dose of dexmedetomidine (a mild sedative) at night can prevent delirium—sudden confusion and disorientation—in older adults after heart surgery. Researchers enrolled 504 patients aged 60-89 who had heart surgery with a heart-lung machine. Th…

This study tested two medications, dexmedetomidine and lidocaine, given during breast removal surgery to control pain right after the operation. Forty women took part, and researchers measured how long it took for them to need extra pain medicine. The goal was to find which drug …

This study tested whether giving a combination of two sedative drugs (dexmedetomidine and esketamine) at night can improve sleep quality for adults in the intensive care unit who need a breathing machine or high-flow oxygen. Researchers measured sleep stages using brain monitorin…

This study tested two different sedation combinations to see which works best for removing a Double-J ureteral stent, a common urology procedure. Sixty adults received either propofol alone or propofol plus dexmedetomidine or midazolam. The goal was to find the safest and most ef…

This study tested a new mix of pain medicines (dexmedetomidine, esketamine, and ropivacaine) against the standard mix (sufentanil and ropivacaine) for epidural pain relief during childbirth. 300 pregnant women took part to see if the new combination works as well and is safer for…

This study tested two different doses (5 µg and 10 µg) of the drug dexmedetomidine, added to a standard spinal anesthetic, in 60 women having planned C-sections. The goal was to see which dose provides longer pain relief and muscle relaxation without causing more side effects. Re…

This study looked at adding dexmedetomidine to a standard numbing medicine for a nerve block after C-section. 80 pregnant women received the block after spinal anesthesia. The goal was to see if the addition would make pain relief last longer, reduce recovery time, and lower the …

This study tested whether breathing in a mist of dexmedetomidine before surgery could prevent dangerous spikes in heart rate and blood pressure during intubation and the start of laparoscopic bariatric surgery. 90 obese adults (BMI 30-45) took part. The goal was to see if this si…

This study compared two sedative drugs, remimazolam and dexmedetomidine, to see which better prevents confusion (delirium) after chest surgery in patients aged 60 and older. Delirium is common after surgery and can slow recovery. The goal was to find a safer option with fewer sid…

This study looked at 60 children aged 3-8 years who needed a procedure to close a hole in their heart. Researchers compared standard general anesthesia to a lighter sedation using two medicines (dexmedetomidine and ketamine) plus numbing at the catheter insertion site. They measu…

This study tested two drugs, magnesium sulfate and dexmedetomidine, to see which works better for pain control during bladder tumor surgery. 93 adults having surgery under spinal anesthesia took part. Results showed that magnesium sulfate lowered pain scores, delayed the need for…

This study tested three different sedative drugs given as a mist to children aged 3-7 before tonsil surgery. The goal was to see which one helps kids feel calm and separate easily from parents. 60 children took part, and researchers measured sedation levels and anxiety.

This study looked at whether giving a drug called dexmedetomidine during laparoscopic surgery for colorectal cancer helps protect the lungs of patients aged 60 to 84. As people age, their lungs become more fragile, and surgery can make breathing problems worse. The researchers me…

This study tested whether adding a medication called dexmedetomidine to standard pain control could reduce the risk of delirium (sudden, severe confusion) in elderly patients after cancer surgery. Researchers enrolled 1,500 patients aged 65 and older who were having major cancer …

This study looked at whether dexmedetomidine, a drug used in general anesthesia, can protect the inner lining of blood vessels (endothelium) from damage during nose surgery. Researchers measured two markers of vessel damage in 90 rhinoplasty patients. The goal was to see if addin…

This study looked at how dexmedetomidine, a sedative, affects how fast the stomach empties in 80 adults having gallbladder surgery. Researchers used ultrasound to measure stomach volume before and after surgery. The goal was to better understand how this drug might impact safety …

This study looked at 78 adults having major spine surgery to compare two anesthesia approaches. One group received propofol, fentanyl, and dexmedetomidine; the other received propofol, fentanyl, and sevoflurane. The goal was to see which combination better preserved nerve signals…

This study looked at 142 people with hard-to-control high blood pressure who had a procedure to calm overactive kidney nerves. Researchers compared two types of sedation to see which one caused fewer side effects like breathing problems or heart issues. The goal was to find the s…