New epidural mix could make labor safer for moms and babies

NCT ID NCT07145775

Completed Symptom relief Sponsor: Peking University First Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested a new epidural pain relief combination (dexmedetomidine, esketamine, and ropivacaine) against the standard mix (sufentanil and ropivacaine) in 300 women during labor. The goal was to see if the new combo works as well for pain and is safer for newborns. It's a pilot trial to check if a larger study is possible.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexmedetomidine, esketamine, and ropivacaine combination
What this could lead to: If this works, it could offer a safer or equally effective alternative for pain relief during labor, with fewer side effects for mothers and newborns.
What could go wrong: This is a small pilot study, so results may not be conclusive. The new combination might not be as effective or could have unexpected risks compared to the standard treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Labor Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEXMEDETOMIDINE EPIDURAL ANALGESIA ESKETAMINE LABOR PAIN ROPIVACAINE SUFENTANIL

Contacts and locations

Locations

Peking University First Hospital

Beijing, Beijing Municipality, 100034, China

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