New study tests safer dosing of Heart-Stabilizing drug during breathing tube insertion

NCT ID NCT06327399

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two methods of giving the drug dexmedetomidine to 70 adults during intubation (placing a breathing tube). One group received a slow infusion over 10 minutes, the other a quick bolus over 60 seconds. The goal was to see which method causes fewer changes in heart rate and blood pressure. Researchers also tracked any episodes of very slow heart rate or low blood pressure that needed rescue medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Dexmedetomidine

What this could lead to

If it works, this could point toward a safer way to give dexmedetomidine during intubation, reducing heart rate and blood pressure swings.

What could go wrong

This is a small, completed Phase 2 trial with only 70 participants. Results may not apply to all patients, and the drug can still cause slow heart rate or low blood pressure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cairo University Hospitals

    Giza, Giza Governorate, 11562, Egypt