Can a drug cocktail prevent ICU brain fog in seniors?

NCT ID NCT07151716

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 36 times

Summary

This study tests whether combining two sedatives, dexmedetomidine and esketamine, can lower the chance of delirium (sudden confusion) in older patients (60+) after surgery in the ICU. Delirium is common and can lead to worse outcomes. The trial will involve 100 participants and track confusion, sleep quality, and pain for up to 7 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University First Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100034, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.