Learning disability

This trial tests whether Masgutova Neurosensorimotor Reflex Integration (MNRI) therapy can improve fine motor skills in children aged 2-6 with developmental delays. Participants receive either MNRI sessions or standard care for four weeks. The study measures changes in hand funct…

This completed study in Damietta, Egypt, involved 300 children aged 3 to 5 years to find out how common developmental delays are and whether early physical therapy can help. Kids with delays received twice-weekly therapy for six months, focusing on motor, language, and social ski…

This completed study tested a digital app called Poppins Clinical in 306 children with dyslexia or other reading/writing learning disabilities. The app combines musical and cognitive exercises with reading training. One group used the app plus bi-monthly speech therapy, while the…

This pilot trial tested whether taking oral zinc every day for 6 months is safe and doable for people with GNAO1 disorders, a rare genetic condition that causes movement problems, seizures, and developmental delays. 13 participants aged 6 months to 30 years took zinc acetate. The…

This study tested a device called EarliPoint that tracks where children look while watching short videos. The goal was to see if it could help diagnose autism spectrum disorder (ASD) in children ages 2.5 to 7. Nearly 1,000 children participated, and the device's results were comp…

This trial tests whether playing with a rainbow parachute can improve upper arm strength and social-emotional skills in children aged 5 to 8 with developmental delays. Half the children will do parachute games for 8 weeks, while the other half does rhyming activities. Researchers…

This trial tests a 12-week smartphone-based program called PACT, which combines acceptance and commitment training with positive parenting advice, for parents of children with special health care needs. The goal is to see if it can improve parents' mental well-being, psychologica…

This study tests a 12-week online program for mothers of infants (12-36 months old) with SMA Type 1. The program aims to teach mothers how to support their baby's development and improve their own knowledge. Thirteen mothers will take part, with 10 receiving the program and 3 rec…

This study tested whether adding a gentle brain stimulation technique called tDCS to a reading therapy (PMT) could help stroke survivors with aphasia read better. Six people with chronic aphasia took part. The goal was to see if the combination improved reading accuracy more than…

This study tested whether an adapted form of Narrative Exposure Therapy (NET) is acceptable and helpful for adults with mild learning disabilities who have experienced trauma. Thirteen participants completed the therapy, which involved talking through their life events in a struc…

This pilot study tested a 4-week laughter yoga program (8 sessions, 15 minutes each) in 45 adolescents with intellectual or physical disabilities at a special school in Hong Kong. Half did laughter yoga, half got routine care. The goal was to see if laughter yoga could improve mo…

This study tested whether extra tutoring in reading and math can improve skills for first-graders who are behind. 385 students from Nashville public schools were randomly assigned to reading tutoring, math tutoring, combined tutoring, or their usual school program. Tutoring laste…

This study tested a group program to help parents of children with learning or attention difficulties manage stress. About 28 parents took part in either a mind-body resiliency group or a health education group, both held online. The goal was to see if the program was practical a…

This study tested a video-based therapy called Focused Acceptance and Commitment Therapy (FACT) for parents of children with special health needs, like ADHD or autism. The goal was to see if it could reduce stress, anxiety, and depression. 104 parents took part, and the therapy w…

This study tested a dynamic blended learning module for 49 people with pulmonary hypertension, a chronic disease causing symptoms like shortness of breath and fatigue. The program included face-to-face education, regular phone follow-ups, and a video from a patient who successful…

This study tested whether special tinted glasses can reduce visual stress symptoms (like eye strain and reading difficulties) in university students. 72 students with visual stress symptoms wore the glasses and reported their reading speed and symptoms. The goal was to see if the…

This study tested whether using a special listening device (FM system) in class for one school year could improve reading and language skills in 71 Chinese children aged 7–11 with dyslexia. Half the children used a real device, and half used a sham device that looked the same but…

This study tested whether a structured program of therapeutic play activities could improve motor adaptive behavior in 20 Egyptian children aged 5-9 with mild intellectual disability. The children took part in 24 play sessions over 2 months, focusing on core strength, coordinatio…

This study tested a coaching program for families of young children (ages 1.5 to 4.5 years) with suspected or confirmed developmental delays. The program included regular coaching sessions, online education, and peer support over 18 months. Researchers measured whether this appro…

This study tested whether trained dogs can help children who miss a lot of school. 64 students in grades 3-9 with at least 15% absence were randomly assigned to receive either dog-assisted support or standard teaching for 30 minutes twice a week for 10-12 weeks. The goal was to s…

This study follows nearly 600 people with Smith-Magenis syndrome (SMS), a rare genetic condition, to track how their health, behavior, and development change over time. Researchers will perform detailed medical exams, genetic tests, and surveys to better understand the syndrome's…

This observational study looks at whether the types of bacteria living in the gut, along with diet and lifestyle, are linked to a person's risk of catching SARS-CoV-2. It follows over 900 children, their family members, and teachers in Spain for 17 months. Researchers collect sto…

This study investigates how different language treatments affect both language skills and brain function in people with aphasia, a condition that impairs the ability to speak, understand, read, or write after a stroke. Participants will receive therapy targeting naming, spelling,…

This study looked for hidden genetic changes in 10 children with developmental delays who had a balanced chromosomal translocation (a rearrangement of DNA that appears normal under a microscope). Researchers used high-resolution DNA microarrays to check for tiny missing or extra …

This study looked at how Doose syndrome, a rare form of epilepsy, affects children's ability to learn and develop. Researchers followed 9 children and asked their parents about the disease's impact on school and daily life. The goal was to better understand the link between seizu…

This study looked at 128 physiotherapy students to see if taking an academic literacy class helped with their reading, writing, and thinking skills. Researchers compared students who took the class to those who did not using surveys. The goal was to understand if such education b…

This study looked at whether an adaptive e-learning course on urgent medical conditions could reduce anxiety and improve skills in junior doctors starting work in emergency departments. 233 new doctors were randomly assigned to either take the course in their first six weeks or r…

This study looked at how the brain uses 'noise'—random variations in brain cell activity—to help people learn. Researchers tested 47 healthy adults using brain scans and computer models to see if this noise makes learning faster or more efficient. The goal was to understand a bas…

This study compared virtual reality (VR) training to standard classroom teaching for nursing students learning how to triage in a mass casualty incident. 100 nursing students took part. The goal was to see if VR helps them triage more accurately and quickly.

This study looked at whether solving crossword puzzles helps nursing students learn how to give intramuscular injections. 140 students took part, with some solving puzzles about the skill before practicing. Researchers measured their motivation, mental effort, and skill performan…

This study looked at whether children with dyscalculia (a math learning disability) have trouble automating counting procedures rather than recalling math facts. Three children aged 8–11 solved simple addition problems over three years while researchers measured their response ti…

This pilot study tested whether using artificial intelligence to personalize educational games can help nursing students learn better about pregnancy and childbirth. 38 second-year nursing students were split into two groups: one received a standard gamified lesson, and the other…

This study looked at whether a blockchain-powered electronic portfolio helps nursing students track their skills and keep learning. 72 third-year nursing students used either a blockchain e-portfolio or a standard one during their clinical rotation. Researchers measured their cli…

This study looked at whether a special reading program called Reach Out and Read (ROR) could help parents read more often to their babies in the Neonatal Intensive Care Unit (NICU). Researchers surveyed 101 parent-infant pairs before and after the program was introduced. The goal…

This study looked at 15 people with a rare genetic condition called DDX3X syndrome, which can cause intellectual disability and sometimes autism. Researchers used interviews, play-based assessments, and genetic tests to better understand the condition. The goal was to describe th…

This study tested whether a flipped classroom model helps midwifery students learn pregnancy exams better than traditional lectures. 95 students were split into two groups: one used online materials before class, the other had standard teaching. Researchers measured knowledge, pr…

This study used a non-invasive brain stimulation technique called TMS to temporarily quiet a part of the brain involved in language processing. Researchers then tested how well 42 older youth with dyslexia learned and remembered made-up spoken words. The goal was to understand th…

This completed study looked at whether giving doctors access to genetic tests called FirstStepDx PLUS and NextStepDx PLUS helps them diagnose intellectual disability and developmental delay more accurately and cost-effectively. The study involved 217 pediatric neurologists, devel…

This study tested whether midwifery students who practice episiotomy repair in pairs learn better than those who practice alone. 92 students were split into two groups. The paired group worked together on calf tongues, while the control group practiced individually. Researchers m…

This study looked at how speech production helps reading in adults with and without dyslexia. 56 adults completed reading tasks while sucking a lollipop, holding a bite bar, or having their mouth numbed with lidocaine. The goal was to see if these motor tasks change reading speed…

This completed study looked at 500 children aged 5 to 18 to understand how factors around birth, thinking abilities, and social-emotional skills are linked to learning difficulties and developmental disorders like ADHD or autism. Researchers compared children with and without the…

This study looked at whether using games in class helps physiotherapy students learn how to treat patients who are afraid of movement (kinesiophobia). About 94 students took part, with some learning through games and others through standard teaching. The goal was to see if the ga…

This small, completed study looked at how many Hydrus microstent surgeries glaucoma fellows need to perform before they become skilled. Researchers graded videos of surgeries from 5 fellows at three eye centers. The goal was to find the average number of cases needed to reach an …

This study tested whether playing a Gimkit game after a regular lab class helps first-year nursing students learn about the respiratory system. 114 students were split into two groups: one got the game, the other didn't. Researchers measured their motivation and test scores to se…

This study compared two ways of teaching medical students to use microscopes: the traditional method with physical microscopes and a newer digital method using computers. 350 fourth-year medical students took part to see which approach helped them learn better. The goal was to fi…

This study looked at how the brain processes speech sounds in 25 people with language impairment or hearing loss. Researchers used e-learning games or hearing aids to see if these interventions change brain activity. The goal was to better understand the underlying problems and g…

This study tested a 15-week reading program called Sit Together and Read (STAR) for 20 children aged 4-5 who are being raised by relatives (kinship caregivers) because their parents used opioids. The program was designed to improve children's reading skills and help caregivers fe…

This completed study at the NIH enrolled 96 children with known or suspected genetic disorders, including autism and Fragile X syndrome. The main goal was to give clinic staff hands-on experience and explore new research ideas. Participants received medical exams, lab tests, and …

This study followed 500 children with and without developmental delays for five years. Researchers measured their quality of life and participation in activities, and analyzed their genes. The goal was to understand what factors help children thrive. No treatments or intervention…

This study looked at how a specific reading program, called Seeing Stars, affects the brains of 90 children with dyslexia. Researchers used brain scans to measure changes in white matter and a region linked to word recognition. The goal was to understand why some children improve…

This study tested a professional development program for teachers in Early Head Start classrooms. Ten teachers attended workshops and received weekly coaching to improve their use of evidence-based practices. The goal was to see if the training was feasible and acceptable, and wh…

This completed study tested a device called EarliPoint that uses eye-tracking to monitor changes in children with autism spectrum disorder (ASD) or developmental delays. Researchers followed 325 children aged 15-84 months over 180 days to see if the device could detect improvemen…

This study looked at 558 people with congenital hypothyroidism, a rare thyroid condition found in newborns. Researchers examined their genes, medical images, and health records to find links between genetic changes and the type or severity of the disease. The goal is to improve e…

This study tested whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can reduce abnormal brain activity and improve language in children with benign epilepsy with centrotemporal spikes (BECTS). Twenty-two children receive…