The University Of Hong Kong

This study tests whether the drug tranexamic acid (TXA) can prevent brain damage from expanding bleeds. It includes 70 adults with a specific type of brain hemorrhage, selected based on bleed size and location. The goal is to see if this targeted approach reduces early neurologic…

This study tests a new method called PIPAC, which sprays chemotherapy directly into the abdomen during a minimally invasive procedure. It is for 60 adults with stomach, pancreatic, or colorectal cancer that has spread to the lining of the abdomen and cannot be removed by surgery.…

This study tests whether giving a triple blood pressure pill soon after a bleeding stroke can quickly and safely control blood pressure. It includes 140 adults in Hong Kong who are at high risk for another stroke. A special score (TRICH) is used to decide who gets the triple pill…

This pilot study tests if electrical stimulation of the spinal cord can help people with long-term spinal cord injury regain movement and function. Five participants will receive a spinal cord stimulator implant and undergo three phases of stimulation over 9 months, targeting the…

This study looks at whether artificial intelligence (AI) can give personalized toothbrushing and flossing advice as well as a dentist can for people with prediabetes. Prediabetes is a condition where blood sugar is higher than normal but not yet diabetes, and it is linked to gum …

This study tests whether combining immunotherapy with targeted radiation can shrink liver tumors that cannot currently be removed by surgery. The goal is to make these tumors small enough for surgery, which could improve survival. The study will enroll 30 adults with inoperable h…

This study tests whether chat-based text messaging and online education hubs can help Hong Kong teens aged 12-18 reduce how often they drink alcohol and binge drink. About 100 teens who have had alcohol in the past year will use these tools for 3 months. The goal is to see if the…

This study tests whether a mobile health app can help people who have had a bleeding stroke (intracerebral hemorrhage) manage their high blood pressure. About 140 participants will use the app to track and control their blood pressure at home. The goal is to see if the app helps …

This study tests a device called PTeye™ that uses near-infrared light to help surgeons see and protect the parathyroid glands during total thyroid removal. About 210 adults in Hong Kong will be randomly assigned to either standard surgery or surgery with this light assistance. Th…

This study tests a personalized lifestyle program for Chinese adults with metabolic syndrome—a cluster of conditions like high blood pressure and blood sugar that raise heart disease risk. Participants will either receive the tailored program or brief advice, and researchers will…

This study tests a 14-week program called Pathway to Healthy Aging (Path-HA) for older adults (60+) who have at least two risk factors for faster aging, like poor physical function or loneliness. About 1000 participants will either join the program or receive no special care. The…

This study aims to create a quick, easy-to-use test (like a pregnancy test) that can detect toxic substances from certain Chinese herbs (aconite) in urine. Aconite poisoning can cause serious heart and nerve problems, but current lab tests take too long. The test will be tried on…

This study tests an 18-week program where people with mild dementia and their family caregivers do sport stacking (a fast cup-stacking game) together online. The goal is to see if it improves thinking skills, mood, and quality of life for both. About 144 pairs will join, with hal…

This pilot study tests whether a chatbot powered by large language models can help people with metabolic alcohol-related liver disease (MetALD) reduce their alcohol intake. Researchers will enroll 50 adults in Hong Kong to see if the chatbot is easy to use and if participants sti…

This study tests a 16-week partner exercise program for people with mild dementia and their family caregivers. The goal is to improve thinking, mood, and the relationship between the pair. About 236 dyads will be recruited from community centers in Hong Kong.

This study tests whether a special story, used in class, can help young children with autism feel more comfortable during dental checkups. About 106 preschool children will either get the dental story or a general story, and researchers will see if it reduces fear and improves co…

This study looks at whether cognitive behavioral therapy for insomnia (CBT-I) can reduce impulsive behavior and risk-taking in young people aged 12 to 24 who have trouble sleeping. Researchers will measure changes in impulsivity and sleep quality. The goal is to see if improving …

This study tests whether the drug vericiguat can improve blood flow in the tiny vessels of the heart and reduce chest pain. It involves 94 adults aged 40-75 who have stable chest pain but no major blockages in their main heart arteries. Participants will receive either vericiguat…

This study looks at whether music therapy can improve mental health and social connections in university students who feel stressed, anxious, or depressed. Twenty students will either take part in music therapy sessions or listen to music and talk. The goal is to see if music the…

This study tests a 6-week WeChat-based program called SOCIAL_HF for elderly heart failure patients who feel socially frail. Participants join weekly video chats, do health check-ins, and access online resources. Researchers want to see if this improves social connections, self-ca…

This study tests whether a specially designed game can help adults who have gone through major life stress feel more positive and resilient. 50 participants will either play the game for 10 days or be placed on a waitlist. Researchers will check their mental health right after th…

This study tests if showing children a real-time ultrasound image of their tongue movements can help them learn to pronounce sounds correctly. Sixty children with speech sound disorders (who have trouble saying certain sounds) will be randomly assigned to receive this therapy rig…

This study tests a program called BrainLive Connect, where trained volunteers lead fun brain exercises for people with mild to moderate dementia. The goal is to see if these sessions, held over 7 weeks, can improve thinking skills and quality of life compared to usual care. About…

This study tests whether a nurse-supported mobile app for cognitive behavioral therapy can reduce insomnia in people caring for a family member with cancer. About 208 caregivers will either use the app with weekly nurse check-ins or receive standard sleep tips. The goal is to see…

This study tests a parent-led sleep program delivered online for children aged 6-12 with autism and insomnia. The program teaches parents behavioral strategies to improve their child's sleep, with some families getting extra personalized support. Researchers will also check if be…

This study tests an internet-based self-help program called eConquerFear-HK for Chinese cancer survivors who have mild to moderate fear of their cancer returning. About 48 people who finished treatment for early-stage breast or colorectal cancer will try the program. The goal is …

This study tests whether a non-invasive brain stimulation technique called rTMS, followed by intensive arm training, can reduce muscle stiffness (spasticity) in children aged 7–18 with hemiplegic cerebral palsy. Twenty participants will receive either real or sham rTMS over 10 da…

This study tests a new program called Mindful-Breath for people with COPD. It combines mindfulness, breathing exercises, and lifestyle coaching through online group sessions and text messages. The goal is to see if it helps reduce stress and increase physical activity. Sixty adul…

This study compares a nurse-led mind-body program (like gentle movement and breathing) to a friendly chat program for reducing loneliness in older adults living in long-term care homes. About 120 residents aged 60 and older who can speak Cantonese will take part. The goal is to s…

This study tests if a non-invasive brain stimulation technique called tDCS can help young adults (18-35) with mild depression feel better. Participants will receive either real tDCS or a sham (placebo) treatment for 10 sessions over 2 weeks. Researchers will track changes in mood…

This study looks at whether a program called Reach-and-Map can help older adults who are hard to reach improve their quality of life, physical health, memory, and mood. About 5,500 people over age 60 will take part. The program aims to match each person's abilities with their env…

This study looks at whether a special training program for volunteers aged 50 and over can improve their knowledge about dementia, their confidence in caring for people with dementia, and their own quality of life. About 180 volunteers will either take the training or just receiv…

This study tests an artificial intelligence (AI) tool designed to help surgeons locate tiny blood vessels in the skin during reconstructive surgery using a piece of leg bone. The goal is to see if the AI can find these vessels as accurately as surgeons do during the operation, po…

This study aims to see if using a life history calendar helps people recall past mental health issues more accurately. Researchers will ask 2,500 adults in Hong Kong about their mental health, with half using a calendar as a memory aid. The goal is to improve how we measure lifet…

This study explores whether experiencing awe—like witnessing a stunning sunset—can motivate adults to engage in preventive behaviors against infectious diseases, such as getting vaccinated, wearing masks, and social distancing. Researchers will survey 456 adults from Hong Kong, S…

This study looks at whether different exercise programs can help people over 60 stay healthy and active. About 1940 older adults will try activities like football, walking, or home exercises, while a control group does no extra exercise. Researchers will measure physical fitness,…

This study looks at whether exercise, like walking and telehealth coaching, along with smoking cessation advice, can improve the walking ability and lung health of smokers who have early signs of lung trouble. Researchers will follow 90 adult smokers or ex-smokers for 12 months t…