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New rapid test could save lives from toxic chinese herb poisoning

NCT ID NCT07456592

Diagnosis Sponsor: The University of Hong Kong Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to create a simple, fast test (like a pregnancy test) to detect poisonous substances from certain Chinese herbs (aconite) in urine. Current lab tests take too long, delaying treatment. Researchers will test the accuracy of this new device in 90 adults who may have been exposed to these toxic herbs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The patient participants are recruited from 3 sources. The Aconite Poisoned Group will include adult patients who present to the emergency departments of Queen Mary Hospital or United Christian Hospital and are reported to the Hong Kong Poison Control Centre for acute aconite poisoning. The Aconite Therapeutic Group will include adult patients who have therapeutic use of aconite in Chinese Medicine Clinics. The Control Group will include adult emergency department patients who have no exposure to aconitine, benzoylaconine, or aconine within 30 days and no clinical evidence of aconite toxicities

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria (Aconite Poisoned Group): * adult patients aged 18 years or above * clinical presentations consistent with acute aconite poisoning, including neurological, gastrointestinal, or cardiovascular symptoms * exposure to aconite alkaloids within 3 days Exclusion Criteria (Aconite Poisoned Group): * refusal of informed consent for urine collection * alternative explanations for clinical presentations Inclusion Criteria (Aconite Therapeutic Use Group): * adult patients aged 18 years or above * documented history of using aconite for therapeutic purposes, as prescribed by a qualified practitioner in a Chinese medicine clinic * exposure to aconite alkaloids within 3 days Exclusion Criteria (Aconite Therapeutic Use Group): \- Refusal of informed consent for urine collection. Inclusion Criteria (Control Group): * adults aged 18 years or above * no documented history of exposure to aconitine, benzoylaconine, or aconine within 30 days * no clinical evidence of aconite toxicities Exclusion Criteria (Control Group): * refusal of informed consent for urine collection * recent history of poisoning or overdose from any other substances within 30 days

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Conditions

The condition(s) this trial relates to.

poisoning

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aconite poisoning

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Accident and Emergency Department, Queen Mary Hospital

    RECRUITING

    Hong Kong, Hong Kong

  • Accident and Emergency Department, United Christian Hospital

    RECRUITING

    Hong Kong, Hong Kong