The University Of Hong Kong

This pilot study tests whether high-dose vitamin D can help the body clear blood clots in the brain after a hemorrhagic stroke. Forty adults with a recent brain bleed will receive either vitamin D or standard care. Researchers will measure how fast the blood clot shrinks and chec…

This study tests a program that combines brief advice, nicotine replacement therapy (like patches or gum), and text-message support to help smoking parents quit. The goal is to reduce children's exposure to secondhand smoke. About 1,200 smoking parents in Hong Kong who live with …

This study tests a social work program called Project ReBond for people serving their first or second prison sentence in Hong Kong. The program includes workshops and counseling before release, plus support like job help and mentoring after release. Researchers will track 300 par…

This study looks at whether restarting blood thinners (DOACs) right after colonoscopy polyp removal is as safe as waiting two days. About 194 adults on DOACs who need a colonoscopy will be randomly assigned to restart their medication on the same day or two days later. The goal i…

This study tests whether the drug tranexamic acid can prevent brain bleed expansion in people with a type of stroke called intracerebral hemorrhage. The researchers are using new criteria to select patients most likely to benefit, based on bleed location and size. About 70 adults…

This study tests a device called PTeye™ that uses near-infrared light to help surgeons see and protect tiny parathyroid glands during total thyroid removal. About 210 adults in Hong Kong will be randomly assigned to standard surgery or PTeye™-assisted surgery. The goal is to see …

This study looks at whether using artificial intelligence during a colonoscopy can reduce the chance of developing advanced colon polyps later on. Researchers will follow 404 people who previously had either an AI-assisted or a standard colonoscopy. The goal is to see if the AI a…

This study tests a new method called PIPAC, which sprays chemotherapy directly into the abdomen as a fine mist. It is for people with stomach, pancreas, or colorectal cancer that has spread to the lining of the abdomen. The goal is to see if this approach can control the cancer a…

This study tests whether a combination of two drugs (levonorgestrel and piroxicam) works better than the standard emergency contraceptive ulipristal acetate at preventing pregnancy. About 980 women aged 18-45 who need emergency contraception within 5 days of unprotected sex will …

This study tests whether adding a hormone drug called Decapeptyl to standard IVF treatments can increase the number of live births. About 784 women under 43 with subfertility will receive either the drug or a placebo during egg retrieval and embryo transfer. The goal is to see if…

This study tests if a mobile health app can help people who had a bleeding stroke better control their blood pressure. About 140 participants will use the app to track their numbers and get health tips. The goal is to see if the app helps more people reach safe blood pressure lev…

This study compares personalized oral hygiene advice from an AI app versus a human dentist in 148 adults with prediabetes and gum disease. The goal is to see if AI can improve gum health and blood sugar levels as effectively as a dentist. Participants will be followed for 9 month…

This study tests whether a scoring tool (TRICH score) can help doctors decide which patients who had a bleeding stroke should start three blood pressure medicines right away. The goal is to quickly lower blood pressure and reduce the risk of another stroke. About 140 adults in Ho…

This pilot study tests whether combining immunotherapy with targeted radiation can shrink liver tumors enough to allow surgery in patients whose cancer was previously too advanced to operate. About 30 adults with unresectable hepatocellular carcinoma will receive the treatment. T…

This study tests whether using a wearable fitness tracker, alone or with health coaching, helps adults aged 40+ with central obesity (belly fat) become more active and improve heart health markers. 133 participants will be split into three groups: one gets a Fitbit with coaching,…

This study is testing a new way to help women reduce their alcohol use. Participants will get brief counseling, daily check-ins via a phone app, and join a private social media support group. The goal is to see if this approach is practical and helpful for women who are at-risk d…

This small pilot study is testing whether electrical stimulation of the spinal cord can help people with long-term spinal cord injury regain movement and function. Five participants will receive a spinal cord stimulator implant and go through three phases: stimulation of the lowe…

This study tests whether adding diquafosol eye drops to standard treatment helps people with moderate-to-severe vernal keratoconjunctivitis (a serious eye allergy). About 94 participants aged 6 and older will receive either diquafosol plus cyclosporine or cyclosporine alone. Rese…

This study tests a tailored lifestyle program for 152 Chinese adults with metabolic syndrome, a cluster of conditions like high blood pressure and blood sugar. Participants receive either the program or brief advice, with health changes measured over 20 weeks. The goal is to see …

This study is testing whether artificial intelligence can accurately diagnose spinal deformities like scoliosis by analyzing photos of a person's bare back. Researchers will enroll 2,500 participants with various spinal conditions and compare the AI's assessment to standard X-ray…

This study is looking for markers in blood and saliva that can quickly tell if a person is having a stroke, and what kind. Researchers will collect samples from 650 adults with suspected stroke within 24 hours of symptoms. The goal is to develop a fast, accurate test to help emer…

This study tests whether a portable electronic stethoscope, combined with machine learning, can accurately detect valvular heart disease. About 125 people with and without the condition will use the device and also receive standard heart tests. Researchers will compare the device…

This study aims to create a simple, non-invasive test to detect early signs of nerve damage in people with degenerative cervical myelopathy (DCM), a condition that affects balance and coordination. Researchers will test 100 adults aged 50 and older who have evidence of DCM on sca…

This study tests whether artificial intelligence (AI) can help doctors spot more stomach growths (neoplasms) during a standard upper endoscopy. About 1,000 adults aged 40 and older will be randomly assigned to either a regular high-definition scope or one assisted by AI. The goal…

This study aims to create a simple, fast test (like a pregnancy test) to detect poisonous substances from certain Chinese herbs (aconite) in urine. Current lab tests take too long, delaying treatment. Researchers will test the accuracy of this new device in 90 adults who may have…

This study tests whether a single injection of a GLP-1 drug (dulaglutide), given 1 to 14 days before planned non-cardiac surgery, can reduce heart muscle injury in 372 adults at risk. Participants are randomly assigned to receive the drug or standard care. The goal is to see if t…

This study tests whether a 14-week elastic band resistance training program can improve muscle mass, strength, and physical function in heart failure patients aged 50 and older who also have sarcopenia (age-related muscle loss). Researchers will measure changes in muscle, symptom…

This study tests whether using ultrasound to show tongue movements on a screen can help children with speech sound disorders pronounce sounds better. Sixty children will be randomly assigned to get the therapy right away or wait a few weeks. The goal is to see if this visual feed…

This study tests a 16-week partner exercise program called BUDPA for people with mild dementia and their family caregivers. The program includes group training and home practice to improve thinking, mood, and relationship quality. Researchers will follow 236 pairs to see if the p…

This study tests whether 8 weeks of mindfulness classes, taken together by people with Parkinson's and their family caregivers, can reduce negative emotions like stress, anxiety, and depression. About 200 Chinese patient-caregiver pairs will either take the classes or continue us…

This study tests whether a special 'social story' about dental visits, used in preschool classrooms, can help autistic children feel less anxious and more cooperative during dental checkups. About 106 Hong Kong preschoolers with autism will be split into two groups: one gets the …

This pilot study tests whether a combination of chat-based text messaging and an online education hub can reduce alcohol consumption and binge drinking in teenagers. Researchers in Hong Kong will enroll 100 adolescents aged 12-18 who have had alcohol in the past year. The program…

This study tests whether a fun, at-home cup stacking program can improve thinking, mood, and quality of life for people with mild dementia and their family caregivers. Over 18 weeks, 144 pairs will either learn sport stacking together or receive basic dementia education. The goal…

This study tests a 6-week WeChat-based program called SOCIAL_HF for elderly heart failure patients who feel socially frail. Participants join weekly video chats, do group tasks, and track daily health. The goal is to see if this online support improves social connections, self-ca…

This study tests whether narrative therapy—a type of counseling that helps people reshape their personal stories—can reduce mental distress, depression, and anxiety in young people aged 12 to 24 in Hong Kong who are struggling with moderate mental health concerns. About 770 parti…

This study tests whether cognitive behavioral therapy for insomnia (CBT-I) can reduce impulsivity and risk-taking in young people aged 12-24 who have trouble sleeping. Researchers will measure changes in impulsive behavior and sleep quality. The goal is to see if improving sleep …

This study tests whether a non-invasive radiofrequency treatment, combined with a standard gland-clearing procedure, can improve tear stability and reduce symptoms in people with stubborn dry eye caused by meibomian gland dysfunction. About 112 adults will be randomly assigned to…

This study tests whether automated, personalized text messages can reduce mood and behavior symptoms in people with mild cognitive impairment (MCI). Researchers will enroll 160 adults aged 50 and older with early memory issues and mild behavioral symptoms. Participants receive da…

This study tests an internet-based self-help program called eConquerFear-HK for Chinese cancer survivors who have mild to moderate fear of their cancer coming back. About 48 people who finished treatment for early-stage breast or colorectal cancer will try the program. The goal i…

This study tests a strength-based exercise program that seniors can do at home after a hospital stay. The goal is to help them regain physical function and reduce frailty. Researchers will enroll 256 people aged 60 and older who are at risk of losing function after being in the h…

This study compares a nurse-led mind-body program (including mindful breathing, stretching, and movement) to a befriending intervention for reducing loneliness in older adults living in long-term care. 120 residents aged 60 and older who can communicate in Cantonese/Chinese will …

This study tests a new program called Mindful-Breath for people with chronic obstructive pulmonary disease (COPD). The program combines mindfulness, breathing exercises, and lifestyle coaching through group sessions and chat support. Researchers want to see if it is feasible and …

This study aims to identify and support hidden caregivers of older adults in Tai Po. Caregivers who are not currently using respite services will receive a combination of in-home respite, social worker follow-up, crisis management, and volunteer phone check-ins based on their nee…

This study tests a program called COPE, designed to help family caregivers of people with dementia reduce stress, depression, and negative emotions. The program combines mindfulness and cognitive behavioral therapy, and can be done in person or online. Researchers will compare CO…

This study looks at whether music therapy can improve mental health and social connections in university students who feel stressed, anxious, or depressed. Twenty students will be randomly assigned to either music therapy sessions or a non-therapeutic music listening group. Resea…

This study tests a health chat program designed to help people with two or more heart-related conditions (like high blood pressure, diabetes, or heart disease) improve their lifestyle and well-being. About 232 adults will either use the chat program or receive usual care. Researc…

This study tests whether a non-invasive brain stimulation technique called tDCS can improve mood and motivation in young adults (18-35) with mild depression. Participants will receive either real tDCS or a sham (placebo) treatment for 10 sessions over 2 weeks. Researchers will tr…

This study tests a parent-led sleep program delivered online for children aged 6-12 with autism and insomnia. About 195 families will join, with some getting extra personal support. The goal is to see if the program improves the child's sleep, daytime behavior, and also helps par…

This study tests a group-based program for families of individuals with special health care needs. The program focuses on promoting psychological flexibility and value-guided living rather than changing distressing thoughts. Researchers will measure changes in stress, well-being,…

This study tests a 12-week program called ENACT for people with mild cognitive impairment (mild memory problems) and hearing loss. The program combines hearing exercises, thinking games, and support from nurses, peers, and family. Researchers want to see if it improves memory, at…

This study tests whether a nurse-supported mobile app that teaches healthy sleep habits can reduce insomnia in people caring for a family member or friend with cancer. About 208 caregivers will either use the app for 6 weeks with weekly nurse check-ins or receive basic sleep tips…

This study tests three different doses of a long-acting numbing medicine (liposomal bupivacaine) injected into a nerve block in the thigh to control pain after total knee replacement. About 177 adults having robotic knee surgery will be randomly assigned to receive one of the dos…

This study tests whether pairing a non-invasive brain stimulation technique (rTMS) with a computer-based thinking exercise can reduce negative thought patterns and mild-to-moderate depression symptoms. About 180 adults with depression will receive either real or fake rTMS, combin…

This study tests whether a non-invasive brain stimulation technique called rTMS, followed by intensive arm training, can reduce muscle stiffness (spasticity) in children aged 7–18 with hemiplegic cerebral palsy. Twenty participants will receive either real or sham rTMS over 10 da…

This study tests a new risk model designed to predict severe side effects from cancer treatments in people aged 65 and older. Participants will either receive usual care or have their treatment plan adjusted based on their risk level, with closer monitoring for those at higher ri…

This study tests if acupressure can reduce coughing and related symptoms like shortness of breath and fatigue in people who have had lung cancer. Eighty participants will either receive acupressure for 8 weeks or get an education booklet. The goal is to see if acupressure improve…

This study tests a program called BrainLive Connect, where trained volunteers lead fun mental activities for people with mild to moderate dementia. The goal is to see if these sessions, held over 7 weeks, can improve thinking skills and quality of life compared to usual care. Abo…

This study tests a chatbot called Digi-Coach to see if it can reduce physical and emotional distress in people receiving radiotherapy for head and neck cancer. About 138 adults will either use the chatbot alongside standard nursing care or receive usual care alone. The goal is to…

This study tests whether a chatbot powered by large language models can help people with metabolic alcohol-related liver disease (MetALD) reduce their alcohol intake. About 50 adults in Hong Kong will use the chatbot for counseling. The main goal is to see if the approach is prac…

This study tests whether the drug vericiguat can improve blood flow in the tiny vessels of the heart and reduce chest pain. About 94 adults aged 40-75 with stable chest pain but no major blockages will take the drug or a placebo. The main goal is to see if heart blood flow improv…

This study tests whether a training program for volunteers aged 50 and over can improve their knowledge about dementia, confidence in caring for people with dementia, and overall quality of life. 180 volunteers will either receive 80-90 hours of BrainLive Coach training or just e…

This study tests whether personalized exercise programs—like football, walking, or home-based workouts—help people over 60 stay healthy and independent. Nearly 2,000 participants will be assigned to different exercise types or a control group. Researchers will track physical abil…

This study aims to create better criteria for deciding when to operate on Chinese patients with degenerative cervical myelopathy, a condition where the spinal cord is compressed. Researchers will test 100 surgical candidates using simple physical performance tests like hand grip …

This study is checking how well a new version of a mental health survey (CIDI 5.0) can identify people with depression, anxiety, and PTSD. Researchers will compare the survey results with a detailed clinical interview in 300 adults living in Hong Kong. The goal is to see if the s…

This study tests whether using a life history calendar—a simple grid that helps people recall important life events—can improve the accuracy of mental health surveys. Researchers in Hong Kong will ask 2,500 adults about their lifetime experiences with conditions like depression, …

This study is collecting blood and saliva samples from 2000 adults who come to the emergency room with a suspected respiratory infection. The goal is to build a biobank and use advanced analysis to better understand these infections, which could lead to improved diagnosis and tre…

This study explores whether experiencing awe—through a nature picture puzzle—can increase adults' willingness to engage in prosocial preventive behaviors like vaccination, mask-wearing, and social distancing. Researchers will recruit 456 adults from Hong Kong, Singapore, and ten …

This study looks at whether a program called Reach-and-Map helps older adults who are hard to reach stay healthy and independent. Researchers will measure quality of life, physical function, memory, loneliness, and depression in 5,500 participants aged 60 and older. The program a…

This study tests an artificial intelligence (AI) tool that helps surgeons locate tiny blood vessels called skin perforators, which are crucial for a type of reconstructive surgery using a bone and skin flap from the leg. The AI analyzes CT scans to find these vessels faster and m…

This study is looking at whether low-dose CT scans can find lung cancer early in people who have a parent, sibling, or child with lung cancer. The study includes 1,520 people aged 50 to 75, both smokers and non-smokers. Researchers want to see how many cases of lung cancer are fo…

This study tests whether a specially designed game can help adults who have gone through major life stress feel more positive and resilient. Sixty participants will be split into three groups: one plays the game, one gets standard mental health education, and one waits. Researche…

This study tests whether a nurse and allergist working together can safely and effectively remove incorrect penicillin allergy labels from patients' records. About 440 people with a penicillin allergy label will be evaluated using this team approach or the standard allergist-only…

This study tests whether a smartphone app (DigitHeart-2) can accurately predict heart structure and function from a simple ECG picture. About 478 adults who need an echocardiogram will have their ECG photo analyzed by the app, and the results will be compared to the standard ultr…

This study looks at whether exercise, like walking and telehealth coaching, along with smoking cessation advice, can improve the lung function of smokers who already have early signs of lung trouble. Researchers will track 90 adults for a year to see if these steps help prevent c…

This study tests a 14-week program called Path-HA designed to help older adults (60+) who are at risk of aging faster than normal. The program includes health education and support to improve quality of life, strength, and balance. 1000 participants will be randomly assigned to e…