POST TRAUMATIC STRESS DISORDER

This small study tested whether transcranial magnetic stimulation (TMS) can lower blood pressure and ease PTSD symptoms in women aged 18-44 who have both conditions. Four participants received 30 TMS sessions over 6 weeks. Researchers measured changes in 24-hour blood pressure an…

This study followed 44 people with PTSD who had already completed a prior methylone (TSND-201) trial. Over 52 weeks, researchers checked their symptoms and safety each month. If PTSD symptoms returned, participants could receive more methylone treatment. The goal was to see if th…

This study tested whether adding a social support program to standard therapy helps trauma-affected refugees with PTSD. 196 unemployed refugees received either standard treatment or standard treatment plus collaboration with municipal social services. The goal was to improve dail…

This study tested a drug called methylone in 62 adults with severe PTSD. Participants took methylone capsules once a week for 3 to 4 weeks. Researchers measured changes in PTSD and depression symptoms to see if the drug is safe and helpful.

This study tested a short virtual reality program called SHINE-VR for 6 adolescents aged 12-17 who had experienced sexual abuse and felt trauma-related shame. The program included three VR sessions focused on psychoeducation and sharing feelings in a virtual group. Researchers me…

This study looked at whether a web-based program called webSTAIR, which teaches skills to manage emotions and relationships, is feasible and helpful for people with PTSD who are on a waitlist for behavioral health treatment. Seventy adults from a hospital clinic in Boston took pa…

This study tested whether a structured, moderate-intensity aerobic exercise program could reduce PTSD symptoms and improve sleep quality in earthquake survivors. 82 adults living in temporary shelters after the February 2023 earthquake took part in supervised group exercise sessi…

This study tested whether a simple writing therapy, done over video calls, could help prevent or reduce PTSD in women who recently experienced sexual assault. Thirty women who visited a Sexual Assault Nurse Examiner (SANE) clinic within 7 days of the assault took part. The therap…

This study tested whether interpersonal psychotherapy (IPT) works as well as two established therapies—prolonged exposure and relaxation—for people with chronic post-traumatic stress disorder (PTSD). About 110 adults with at least moderately severe PTSD took part. The goal was to…

This study looked at whether mindfulness training could help veterans with PTSD who struggle with anger and aggression. 61 veterans took part. The goal was to see if learning to focus on the present moment could help them control angry feelings and reduce aggressive behavior.

This study tested a program called EMPOWER for veterans who had already completed trauma-focused therapy for PTSD and seen improvement. The program gave veterans a workbook and four therapist check-ins over 12 weeks to help them keep using therapy skills, manage symptoms, and sta…

This study tested a mobile app called BounceBack Now (BBN) to help people with post-traumatic stress disorder (PTSD) manage their symptoms. The app provides self-help tools for depression, anxiety, sleep problems, and PTSD. Researchers worked with 29 participants in primary care …

This study looked at whether 6 months of supervised exercise training could reduce PTSD symptoms and improve physical health in older veterans with PTSD. 80 veterans took part, with one group doing exercise and another receiving health education. The goal was to see if exercise c…

This completed study tested a unique approach for veterans with PTSD: combining a racecar simulator with psychological skills training like self-talk, goal-setting, and biofeedback. The goal was to help veterans better regulate their emotions and improve quality of life. Only one…

This study looked at whether art therapy can help people with trauma who have trouble talking about their experiences. 38 adults with trauma symptoms like nightmares or anxiety took part. They used art materials to express feelings and work through memories. The goal was to see i…

This study tested a modified version of Goal Management Training, called Trauma-Informed GMT, designed to be more sensitive to people with PTSD. 33 adults with PTSD took part in a 9-week online group program. Researchers measured changes in thinking skills and PTSD symptoms right…

This study tested if Written Exposure Therapy (WET) can work when delivered online in a group setting for military and police with PTSD. 29 people took part to see if the treatment was acceptable and if it reduced PTSD and depression symptoms. The goal was to find a more accessib…

This study tested three ways to deliver Acceptance and Commitment Therapy (ACT) for adults aged 20-40 with mild to moderate PTSD in Pakistan. Participants were split into three groups: standard clinic therapy, clinic therapy with a supporting web app, and fully online therapy wit…

This small pilot study tested the Safe and Sound Protocol (SSP), a passive listening program, in 45 adults with PTSD or anxiety. Participants listened to specially filtered music as a 'neural exercise' to help regulate their body's stress response. The study measured changes in P…

This study tested whether methylone, a substance similar to MDMA, can safely reduce PTSD symptoms in adults. 79 participants with moderate to severe PTSD received either methylone or a placebo once a week for four weeks, then were followed for six more weeks. The goal was to see …

This study tested a talking therapy called Cognitive Processing Therapy (CPT) in 36 adults who experienced the 2023 earthquakes in Turkey. The goal was to see if CPT could reduce symptoms of PTSD, depression, and anxiety, and improve overall well-being. Participants were randomly…

This study tested a type of talk therapy called Acceptance and Commitment Therapy (ACT) to help veterans with PTSD improve their social support and relationships. 107 veterans took part, and the therapy focused on helping them feel less isolated and more connected to family and f…

This study tested a trauma-focused therapy (TF-CBT) for young people aged 8 to 19 who had experienced trauma and had PTSD symptoms. The therapy was delivered in schools to make it easier for students to get help. Researchers also tested a strategy to help school clinicians adopt …

This study tested whether a smartphone-based attention training program can reduce symptoms of post-traumatic stress disorder (PTSD). Over 1,300 adults with significant PTSD symptoms completed 14 sessions of either the active training or a placebo version. Researchers measured ch…

This study tested a 5-week group program called Rare Group Problem Management Plus (PM+) for parents or guardians of children with rare diseases. The program, delivered by video, aims to help with practical and emotional problems like anxiety, depression, and stress. Eight caregi…

This study looked at whether adding a type of talk therapy called prolonged exposure therapy (PET) to standard opioid addiction treatment can help reduce PTSD symptoms. 82 adults with both opioid use disorder and PTSD took part. Some got only addiction treatment, while others als…

This study tested whether minocycline, an antibiotic, could reduce the frequency and intensity of intrusive memories in people with PTSD or cocaine use disorder. 138 adults participated, and researchers measured changes in memory-related brain activity and self-reported distress.…

This study looked at whether giving a special therapy called EMDR to people in the emergency room right after a traumatic event could help prevent post-traumatic stress disorder (PTSD). About 110 adults who were at high risk for PTSD took part. The therapy uses eye movements to h…

This study tested a workshop called STEP-Home for 221 post-9/11 Veterans who had trouble reintegrating into civilian life. The workshop taught skills like emotional control, problem solving, and attention to improve daily function and reduce anger. It was designed as a non-stigma…

This study looked at whether adding lofexidine to standard buprenorphine treatment can improve symptoms of both PTSD and opioid use disorder in veterans. 84 veterans on stable buprenorphine therapy were enrolled. The goal was to see if the combination reduced opioid use and PTSD …

This study looked at whether learning to train a future service dog, along with standard care, can improve symptoms of post-traumatic stress (PTS), traumatic brain injury (TBI), and related issues like anxiety and depression. 156 military members and their families took part. Res…

This study tested a type of group therapy called Resilience-Oriented Therapy (RoT) for adults in Rwanda who were struggling with mental health issues like trauma, depression, anxiety, or anger. 427 people took part, and the therapy was tailored to each person's main problem, such…

This study tested a new way of delivering care for people with anxiety and depression in Danish general practices. 302 adults with conditions like panic disorder, social anxiety, or PTSD took part. The model involved a team of doctors, nurses, and therapists working together, and…

This study tested a program called MOSAIC Plus for pregnant women and mothers of children under 5 who have experienced intimate partner violence and have symptoms of depression or PTSD. The program pairs women with community advocates who provide support and teach skills to impro…

This study tested two online courses designed to help paramedics in Singapore manage stress, anxiety, depression, and burnout during the COVID-19 pandemic. 63 paramedics took part, completing six weekly online modules. The goal was to see which course better improved mental healt…

This study tested whether transcranial magnetic stimulation (TMS) can improve PTSD symptoms and change related brain activity and startle responses. Fifty adults with partial PTSD received TMS treatment. Researchers measured changes in brain scans and skin conductance to see if t…

This study tested a one-day life skills workshop for veterans with mild traumatic brain injury, chronic pain, and mental health conditions like PTSD and depression. The goal was to reduce distress and help them reintegrate into civilian life. 176 veterans participated, and the wo…

This study tested whether adding a mild brain stimulation technique called tDCS to standard trauma-focused therapy can better reduce PTSD symptoms. 63 adults with chronic PTSD took part. The goal was to see if the stimulation helps the therapy work more effectively, offering a ne…

This study looked at whether a natural probiotic called Lactobacillus rhamnosus GG could help veterans with PTSD by reducing inflammation in the body and brain. Researchers measured changes in blood markers, gut health, and PTSD symptoms over time. The goal was to see if this sim…

This study tested whether a simple technique called progressive muscle relaxation training can reduce symptoms of post-traumatic stress disorder (PTSD) in people affected by the February 6 Kahramanmaraş earthquake. 44 adults with PTSD took part. The training involves tensing and …

This completed study from France looked at how often patients and their relatives develop post-traumatic stress disorder (PTSD) after a sudden cardiac arrest. Researchers interviewed 45 people—20 survivors and 20 relatives—within a week of the event and again at 3 months using st…

This study tested a coaching program for doctors to improve communication with Black and Latinx families during hospital rounds. The program taught doctors to be more respectful, collaborative, and trauma-aware. Researchers measured whether families felt more trust and satisfacti…

This study looked at whether a special planning tool, called a POST form, helps older adults (65+) get the medical care they prefer at the end of life. Researchers worked with 389 people, including those with dementia, to see if their treatment matched their wishes. The goal was …

This study aimed to find factors that can predict whether someone will develop post-traumatic stress disorder (PTSD) after a traumatic event like a serious injury or violence. Researchers followed 460 adults who came to the emergency room within a month of trauma and were at mode…

This study looked at the specific symptoms of complex post-traumatic stress disorder (PTSD) compared to regular PTSD. Researchers used questionnaires to measure dissociation, emotional control, and trauma in 300 adults. The goal was to better understand and identify complex PTSD,…

This study followed 14 people who called a crisis hotline after terrorist attacks in Paris, London, Barcelona, and Strasbourg. Researchers asked them to rate how their symptoms of post-traumatic stress and depression changed over time. The goal was to understand what kind of help…

This study looked at how people with post-traumatic stress disorder (PTSD) predict their emotional reactions to future events. Researchers compared 97 participants with and without PTSD to see if those with PTSD tend to expect more intense negative emotions than they actually exp…

This study tested whether a smartphone app could help veterans with serious mental illnesses like schizophrenia and bipolar disorder track their own symptoms. 87 veterans used the app to monitor their activity, sleep, and social interactions. The goal was to see if this data coul…

This study looked at how the COVID-19 pandemic impacted the mental health of 501 nursing home workers in Occitanie, France. Researchers measured rates of post-traumatic stress disorder (PTSD), depression, and burnout using standard questionnaires. The goal was to understand how c…

This study tested the safety and processing of methylone in 40 healthy adults aged 25 to 55. Participants received a single, increasing dose to measure how the drug moves through the body and to check for side effects. The results will inform future research on methylone as a pos…

This study looked at how mindfulness-based cognitive therapy (MBCT) changes brain activity in 61 adults with PTSD. Participants received either MBCT or a mind-body comparison therapy, and researchers used fMRI scans to measure brain connectivity before and after treatment. The go…

This study followed survivors of the 2015 Paris terrorist attacks for up to 6 years, using brain scans to see how trauma affects the brain's ability to control unwanted memories. Researchers compared 216 survivors with people who were not exposed to the attacks. The goal was to u…

This study looked at how negative emotions and stress influence alcohol use in 81 women veterans, including those with PTSD. Researchers measured cravings, heart rate, and drinking patterns, and also examined how these effects change across the menstrual cycle. The goal was to be…

This study looked at how cannabinoids influence the way the brain processes fear in people with PTSD. Researchers measured brain activity and fear responses in 86 adults, including those with PTSD, trauma-exposed individuals without PTSD, and healthy controls. The goal was to und…

This study looked at how people with PTSD pay attention to their surroundings. Researchers used a change blindness test to see if patients are quicker to notice changes, especially emotional ones. 80 adults with PTSD and healthy controls participated. The goal was to understand t…

This study looked at a program called KEEP that trains foster and kinship parents to better support children in their care. The goal was to see if the program could reduce depression, anxiety, PTSD, self-harm, and behavior problems in youth from Native, Hispanic, Black, and LGBTQ…

This study created and tested a mobile app called VetEd for student veterans dealing with mental health issues like depression, PTSD, or anxiety. The goal was to help them manage academics, mental health, and find resources. Researchers worked with 13 veterans to see if the app w…

This study used MRI and PET scans to examine the glutamate system in people with major depression, PTSD, or bipolar disorder. Researchers aimed to understand how a specific glutamate receptor (mGluR5) relates to these conditions. 180 participants aged 18-70 completed cognitive te…