POST TRAUMATIC STRESS DISORDER

This study follows about 1,756 adults who were part of a larger trial and received either ketamine or etomidate during emergency intubation. Researchers want to see if ketamine can reduce PTSD symptoms one year later, since it may block the brain's formation of traumatic memories…

This study looks at whether giving people with PTSD a personalized mix of gut bacteria (called pharmabiotics) can help their mental health. The researchers will track changes in PTSD symptoms, anxiety, depression, and thinking skills over 14 days. The goal is to see if fixing the…

This study tests whether a trauma-informed program called Strength at Home works better than the usual state-approved program for reducing intimate partner violence. About 800 men who are court-ordered to attend such programs, along with their partners, will take part. Researcher…

This study tests whether a short, modified exposure therapy given soon after rape can prevent post-traumatic stress disorder (PTSD) in women. About 166 women who have experienced sexual assault will be randomly assigned to either the brief therapy or standard care. The goal is to…

This Phase 2 study tests whether fluoxetine (Prozac) can reduce PTSD symptoms in active-duty service members, veterans, and civilians. About 200 participants will receive either fluoxetine or a placebo for 12 weeks. The main goal is to see if PTSD severity decreases and to monito…

This pilot study tests whether a mobile neurofeedback device (MUSE 2) can help new mothers who have experienced trauma feel better and reduce stress. Forty mothers with PTSD symptoms will use the headband at home for 12 weeks, receiving audio feedback to train their brains to sta…

This study tests a therapy called Deep Brain Reorienting (DBR) for people with PTSD. DBR helps patients focus on physical tension linked to traumatic memories. 234 adults will be randomly assigned to either DBR or a waitlist, and researchers will measure changes in PTSD symptoms.

This study tests whether a stellate ganglion block—an injection of anesthetic near nerves in the neck—can reduce PTSD symptoms and change brain activity. 79 adults with chronic PTSD will receive either the real injection or a placebo (saline). Brain scans and symptom checklists b…

This pilot study tests whether repetitive transcranial magnetic stimulation (rTMS) can reduce alcohol cravings in veterans who also have mild traumatic brain injury or PTSD. Twenty veterans will receive either real or placebo rTMS over 10 sessions in two weeks. The goal is to see…

This study looks at whether unlicensed professionals can successfully provide cognitive behavioral therapy (CBT) to patients in a general hospital. It includes 250 adults with conditions like anxiety, depression, OCD, and PTSD. The goal is to see if this approach improves psychol…

This study tests a community-based program called CRISOL Mente to help Latinos in the Philadelphia area who are struggling with depression, anxiety, or PTSD. The program offers culturally sensitive support to overcome barriers like language, cost, and stigma. About 603 adults wil…

This study looks at whether a brain-training technique called neurofeedback can help new mothers who have experienced trauma feel better and manage their emotions. Twenty postpartum women with trauma-related symptoms will try the training alongside their usual care. The goal is t…

This study tests a short therapy called Brief Prolonged Exposure (Brief PE) to see if it can reduce post-traumatic stress in people who have had a spinal cord injury. About 200 adults in inpatient rehab will either get this therapy or standard care. The goal is to ease PTSD sympt…

This study aimed to see if a voice-changing device could make exposure therapy easier for people with PTSD. Patients would read their trauma story aloud while software altered their voice's emotional tone, hoping to reduce distress. The study was withdrawn before any participants…

This study compares a new, shorter therapy for Post-Traumatic Stress Disorder (PTSD) to standard treatments. Researchers want to see if the brief approach works just as well at reducing symptoms. About 82 adults with PTSD will take part. The main goal is to measure changes in PTS…

This study aimed to see if the blood pressure drug propranolol could help teenagers with PTSD by weakening traumatic memories during a therapy session. It planned to enroll teens aged 12 to 18 who had PTSD for at least three months. However, the trial was withdrawn before any par…

This study tests an experimental drug called SLS-002 to see if it can safely reduce PTSD symptoms in active-duty service members, veterans, and civilians. About 200 participants will receive either the drug or a placebo twice a week for 8 weeks, then once a week for 4 more weeks.…

This study tests whether a stellate ganglion block—a numbing injection in the neck—can quickly reduce PTSD symptoms in veterans. About 410 veterans who still have PTSD after trying standard treatments will receive either the real injection or a sham (fake) one. Researchers will m…

This early-stage study tests whether psilocybin (the active ingredient in magic mushrooms) can safely help adults with long-term PTSD who are already taking antidepressants. Twenty participants will receive psilocybin, and some will also get trauma-focused talk therapy. The goal …

This study aimed to test a short program called PCIP (Primary Care Intervention for PTSD) for teenagers with post-traumatic stress disorder. The program included relaxation techniques and education, delivered via telehealth. However, the trial was withdrawn before enrolling any p…

This study looks at brain changes in people with major depression or PTSD using special PET scans. Researchers want to see if a single dose of ketamine can reverse loss of brain connections. About 130 adults aged 18-70 will have MRI and PET scans, with some receiving ketamine dur…

This study aimed to test the safety and feasibility of a new brain imaging technique called Echo-Focusing in people with hard-to-treat neurological and psychiatric disorders like essential tremor and depression. It was designed for adults aged 20 to 80 who had not responded to st…

This study looks at how young people aged 15 to 24 use the internet and how it relates to their mental health. Researchers will survey 50 participants about their internet habits, emotions, and experiences with cyberbullying. The goal is to better understand connections between o…

This study aimed to see how MDMA changes brain activity in people with PTSD, especially in areas that handle emotions. Researchers planned to give MDMA to a small group and measure brain scans and PTSD symptoms. However, the study was withdrawn before any participants were enroll…

This study explores whether artificial intelligence can analyze speech patterns to help diagnose mental health conditions like ADHD, autism, depression, anxiety, and schizophrenia. Researchers will collect voice samples from 500 people aged 16-60 who are already being evaluated f…